PHR1005

Acetaminophen

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinónimos: 4′-Hydroxyacetanilide, 4-Acetamidophenol, N-(4-Hydroxyphenyl)acetamide, N-Acetyl-4-aminophenol, APAP, Paracetamol
• Fórmula lineal: CH₃CONHC₆H₄OH
• Número de CAS: 103-90-2
• Peso molecular: 151.16
• Beilstein: 2208089
• Número CE: 203-157-5
• Número MDL: MFCD00002328
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329823036
• NACRES: NA.24

Propiedades

• grado: certified reference material; pharmaceutical secondary standard
• Nivel de calidad: 300
• Agency: traceable to BP 371; traceable to Ph. Eur. P030000; traceable to USP 1003009
• familia API: paracetamol, acetaminophen
• CofA: current certificate can be downloaded
• técnicas: HPLC: suitable; gas chromatography (GC): suitable
• mp: 168-172 °C (lit.)
• aplicaciones: pharmaceutical (small molecule)
• Formato: neat
• temp. de almacenamiento: 2-30°C
• cadena SMILES: CC(=O)Nc1ccc(O)cc1
• InChI: 1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)
• Clave InChI: RZVAJINKPMORJF-UHFFFAOYSA-N
• Información sobre el gen: human ... FAAH(2166) , PTGS1(5742) , PTGS2(5743) , TRPV1(7442)

Descripción

Descripción general

Acetaminophen is a drug, which possesses pharmacological properties like antipyretic and analgesic property.[1]

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicación

Acetaminophen may be used as a standard in the determination of acetaminophen in human serum or plasma samples using spectrophotometric technique.[1] It may also be used as a standard in the estimation of acetaminophen in pharmaceutical formulations using high performance liquid chromatography (HPLC).[2][3]

Analgesic.

Nota de análisis

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Otras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAB7782 in the slot below. This is an example certificate only and may not be the lot that you receive.

Productos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H302
• Consejos de prudencia: P264 - P270 - P301 + P312 - P501
• Clasificaciones de peligro: Acute Tox. 4 Oral
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): 364.3 °F - Pensky-Martens closed cup
• Punto de inflamabilidad (°C): 184.6 °C - Pensky-Martens closed cup