This product meets 4X the minimum USP specifications. According to the USP monograph for Pancreatin, the 1X minimum specification is 25 USP units amylase, 2 USP units lipase, and 25 USP units protease per milligram. The calculated protease activity for the 4X preparation then, would be at least 100 units per milligram. This is a calculated value based on the USP monograph and are not reported separately on the Certificate of Analysis.
P1750
Pancreatina from porcine pancreas
4 × USP specifications
Sinónimos:
Pancreatina from hog pancreas
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Productos recomendados
Agency
USP (specifications)
Nivel de calidad
Formulario
powder
actividad específica
4 × USP specifications
contiene
lactose or sucrose as extender (The sucrose used might contain up to 3.25% starch.)
temp. de almacenamiento
−20°C
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Categorías relacionadas
Aplicación
Pancreatin from porcine pancreas has been used:
- for a study to assess the treatment of steatorrhea by lipase supplementation therapy[1]
- for a study to investigate treatment options for pancreatic diabetes in patients experiencing the decompensated stage of chronic pancreatitis[2]
- to safely and effectively remove formalin-fixed tissues from arterial grafts without causing structural damage and loss in fiber integrity [3]
- to assess cleavage by digestive enzymes.
- for in vitro digestibility analysis and to test the sensitivities of cellulolytic bacteria inhibitors.[4]
- along with amyloglucosidase for the in vitro digestion of starch in food samples.[5]
Acciones bioquímicas o fisiológicas
La pancreatina contiene componentes enzimáticos, como la tripsina, la amilasa y las lipasas, las ribonucleasas y las proteasas, producidas por las células exocrinas de páncreas porcino. Esta combinación de enzimas permite hidrolizar las proteínas, el almidón y las grasas. La pancreatina convertirá no menos de 25 veces su peso de almidón de patata en carbohidratos solubles en 5 minutos en agua a 40 °C, digerirá no menos de 25 veces su peso de caseína en 60 minutos a pH 7,5 a 40 °C y liberará no menos de microequivalentes de ácido por minuto por miligramo de pancreatina del aceite de oliva a pH 9,0 y 37 °C.
Palabra de señalización
Danger
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
Órganos de actuación
Respiratory system
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 2
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
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Certificados de análisis (COA)
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Los clientes también vieron
Peter Layer et al.
Pancreas, 26(1), 1-7 (2002-12-25)
Treatment of steatorrhea by lipase supplementation therapy has become more successful in the last decade due to better understanding of the physiology and pathophysiology of the digestive process. Porcine lipase has been the therapeutic standard for several decades and will
David C Whitcomb et al.
Digestive diseases and sciences, 52(1), 1-17 (2007-01-06)
A primary function of the pancreas is to produce digestive enzymes that are delivered to the small intestine for the hydrolysis of complex nutrients. Much of our understanding of digestive enzymes comes from studies in animals. New technologies and the
Cunxi Wang et al.
Regulatory toxicology and pharmacology : RTP, 71(2), 164-173 (2014-12-30)
DroughtGard maize was developed through constitutive expression of cold shock protein B (CSPB) from Bacillus subtilis to improve performance of maize (Zea mays) under water-limited conditions. B. subtilis commonly occurs in fermented foods and CSPB has a history of safe
Asavela Ngalavu et al.
Animals : an open access journal from MDPI, 10(4) (2020-04-17)
Feed fiber composition is usually considered as one of the factors that have an impact on digestive tract microbiota composition. The investigations on the level of fermentation and in-vitro digestibility of different fibers are not well understood. The aim of
Priscila Brigide et al.
Food & function, 10(8), 4802-4810 (2019-07-19)
The present work evaluated the effect of different processes in relation to mineral content and its bioavailability, as well as the effect of phytate and oxalate contents in biofortified beans. The following treatments were evaluated: raw beans (RB), cooked and
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units of pancreatin cas number 8049-47-6
1 answer-
Helpful?
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What is the trypsin activity of this P1750 product ?
1 answer-
This product is not specifically tested for trypsin activity. The material meets USP requirements. This monograph includes testing for protease, amylase, and lipase.
Helpful?
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What is the solubility of p1750 pancreatin in water?
1 answer-
This product is soluble at 7 mg/mL in water and may yield a hazy solution.
Helpful?
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As per USP: Pancreatin contains, in each mg, not less than 25 USP Units of protease activity. I assume that product P1750 contains minimum 100 USP units of protease activity in each mg. What is the maximum USP units of protease activity in P1750 ?
1 answer-
Yes, this is correct. To meet the USP specifications, the protease activity will be less than 100 USP Units/mg.
Helpful?
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