T8657

Trichloressigsäure

suitable for electrophoresis, suitable for fixing solution (for IEF and PAGE gels), ≥99%

• Synonym(e): TCA
• Lineare Formel: Cl₃CCOOH
• CAS-Nummer: 76-03-9
• Molekulargewicht: 163.39
• Beilstein: 970119
• EG-Nummer: 200-927-2
• MDL-Nummer: MFCD00004177
• UNSPSC-Code: 41105319
• PubChem Substanz-ID: 24900550
• NACRES: NB.22

Eigenschaften

• Dampfdichte: <1 (vs air)
• Dampfdruck: 1 mmHg ( 51 °C)
• Assay: ≥99%
• Form: powder or flakes (or crystals)
• Methode(n): electrophoresis: suitable
• Trübung: ≤3 NTU (1 g/ml)
• Brechungsindex: n20/D 1.62 (lit.)
• bp: 196 °C (lit.)
• mp (Schmelzpunkt): 54-58 °C (lit.)
• Löslichkeit: water: 1 g/mL, clear, colorless
• Dichte: 1.62 g/mL at 25 °C (lit.)
• Anionenspuren: chloride (Cl^-): ≤0.001%; nitrate (NO₃^-): ≤0.002%; phosphate (PO₄^3-): ≤5 ppm; sulfate (SO₄^2-): ≤0.02%
• Kationenspuren: Fe: ≤0.0005%; heavy metals (as Pb): ≤0.002%
• Eignung: suitable for fixing solution (for IEF and PAGE gels)
• Anwendung(en): cell analysis
• Lagertemp.: 2-8°C
• SMILES String: OC(=O)C(Cl)(Cl)Cl
• InChI: 1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)
• InChIKey: YNJBWRMUSHSURL-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Trichloroacetic acid (TCA) is produced during the chlorination of water comprising natural organic material. It is a novel reagent used in clinical laboratories for deproteinization of body fluids. In addition, TCA is also used in the treatment of genital warts and acne scars.

Anwendung

Trichloroacetic acid has been used:

• for hydrolysis of DNA isolated from the cell
• for precipitation of glutathione isolated from seminal plasma
• as a fixative in microscopy

Traditionell zur Fällung von Proteinen verwendet. Zur Bestimmung der Proteinkonzentration durch quantitative Fällung. Zum Entkalken und als Fixationsmittel in der Mikroskopie verwendet.

Sicherheitshinweise

• Piktogramme: GHS05,GHS09
• Signalwort: Danger
• H-Sätze: H314,H410
• P-Sätze: P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Gefahreneinstufungen: Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A
• Lagerklassenschlüssel: 8B - Non-combustible corrosive hazardous materials
• WGK: WGK 2
• Flammpunkt (°F): >235.4 °F - closed cup
• Flammpunkt (°C): > 113 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges