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Wichtige Dokumente
Q2876
Chinakrin-Senf -dihydrochlorid
≥85% (HPLC)
Synonym(e):
2-Methoxy-6-chlor-9-(4-bis-[β-chlorethyl]-amino-1-methylbutylamino)-acridin -dihydrochlorid, 9-[4-(Bis-(2-chlorethyl)-amino)-1-methylbutylamino]-6-chlor-2-methoxyacridin -dihydrochlorid
Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
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5 MG
76,10 €
25 MG
293,00 €
100 MG
672,00 €
Alle Fotos(5)
Größe auswählen
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5 MG
76,10 €
25 MG
293,00 €
100 MG
672,00 €
About This Item
Empirische Formel (Hill-System):
C23H28Cl3N3O · 2HCl
CAS-Nummer:
Molekulargewicht:
541.77
Beilstein:
3819822
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352101
PubChem Substanz-ID:
NACRES:
NA.32
Empfohlene Produkte
Assay
≥85% (HPLC)
Lagertemp.
−20°C
SMILES String
Cl[H].Cl[H].COc1ccc2nc3cc(Cl)ccc3c(NC(C)CCCN(CCCl)CCCl)c2c1
InChI
1S/C23H28Cl3N3O.2ClH/c1-16(4-3-11-29(12-9-24)13-10-25)27-23-19-7-5-17(26)14-22(19)28-21-8-6-18(30-2)15-20(21)23;;/h5-8,14-16H,3-4,9-13H2,1-2H3,(H,27,28);2*1H
InChIKey
JETDZFFCRPFPDH-UHFFFAOYSA-N
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Allgemeine Beschreibung
Quinacrine mustard dihydrochloride is a fluorescent acridine dye, also abbreviated as QM. In an aqueous solution, the chloroethyl groups rapidly lose chloride ions yielding aziridinium cations. These readily react with the carboxyl, thiol, and heterocyclic ring nitrogen groups of proteins and nucleic acids, or with other nucleophiles.
Anwendung
Quinacrine mustard dihydrochloride is used to stain metaphase chromosomes. Recent applications include the Q-banding of maize and karyotyping of fish. The dye is also used as a vital stain for trypanosomes.
Signalwort
Danger
H-Sätze
Gefahreneinstufungen
Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Repr. 2 - Resp. Sens. 1 - Skin Sens. 1
Lagerklassenschlüssel
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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Animal in vivo biotinylation studies have demonstrated that thiazole orange (TO) labels the youngest cells in the circulation. TO has since been widely used for the measurement of reticulated platelets. As recent findings suggest that at high concentrations TO also
K Tanaka et al.
Biomedical chromatography : BMC, 3(6), 246-250 (1989-11-01)
A simple and precise method was developed for the separation of nucleosides including modified nucleosides and oligonucleotides. Nineteen kinds of nucleosides were completely separated by HPLC using an ODS column (TSK-gel ODS 80TM) and aqueous mobile phases. The RNA molecule
D Fukushi et al.
Cytogenetics and cell genetics, 92(3-4), 254-263 (2001-07-04)
The DNA of Apodemus argenteus was digested with DraI, and the resultant DraI fragment of highly repetitive DNA was isolated and analyzed by DNA filter hybridization, cloning, sequencing, and fluorescence in situ hybridization (FISH). Southern blot hybridization and nucleotide sequencing
Yong Yu et al.
Proceedings of the National Academy of Sciences of the United States of America, 100(7), 3907-3912 (2003-03-20)
Noncompetitive inhibitors of the nicotinic acetylcholine (ACh) receptors suppress cation flux directly by binding in and blocking the open channel or indirectly by stabilizing closed states of the receptor. The lidocaine derivative QX-314 and the acridine derivative quinacrine act directly
Diagnosis of triploidy in metaphases from uncultured amniocytes.
Vanna Pecile et al.
Prenatal diagnosis, 22(1), 78-79 (2002-01-26)
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What is the Department of Transportation shipping information for this product?
1 Antwort-
Hilfreich?
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Is quinacrine mustard, product Q2876, suitable as a viability stain for platelets?
1 Antwort-
A customer's feedback utlizing the method outlined in Moroi, M. et al., Blood, 88(6), 2081-2092 (1996), stated it performed pretty well, giving a strong green signal using a standard GFP-filter.
Hilfreich?
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