B7166

5-Bromouridine 5′-triphosphate sodium salt

≥93%

• Synonym(e): 5-BrUTP
• Empirische Formel (Hill-System): C₉H₁₄BrN₂O₁₅P₃ · xNa⁺
• CAS-Nummer: 161848-60-8
• Molekulargewicht: 563.04 (free acid basis)
• UNSPSC-Code: 41106305
• PubChem Substanz-ID: 24891977
• NACRES: NA.51

Eigenschaften

• Biologische Quelle: synthetic (organic)
• Qualitätsniveau: 200
• Assay: ≥93%
• Form: powder
• Lagertemp.: −20°C
• SMILES String: OP(OP(OP(O)(O)=O)(O)=O)(OC[C@H]1O[C@@H](N(C=C2Br)C(NC2=O)=O)[C@H](O)[C@@H]1O)=O.[Na]
• InChI: 1S/3Na/q3*+1
• InChIKey: BVPYARCRLTXGBD-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

5-Bromouridine 5′-triphosphate (5-BrUTP) is used to measure transcription via labeling of ribonucleic acids (RNA). RNA or cells labeled via 5-BrUTP incorporation may be detected immunologically with antibodies.[1]

Anwendung

5-Bromouridine 5′-triphosphate (5-BrUTP) is used to measure transcription via labeling of ribonucleic acids (RNA). RNA or cells labeled via 5-BrUTP incorporation may be detected immunologically with antibodies.

5-Bromouridine 5′-triphosphate sodium salt has been used:

• to infer the chromosome intermingling between embryonic stem (ES) cells (differentiated and undifferentiated) and terminally differentiated NIH3T3 cells[2]
• to label nascent RNA in in vivo transcription analysis using fibroblasts[3]
• and transfected MDA-MB-231 cells[4]
• to label RNA for nuclear run-on experiments[5]

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves