BP383

Cytarabin

British Pharmacopoeia (BP) Reference Standard

• Synonym(e): Cytosin β-D-Arabinofuranosid, (β-D-Arabinofuranosyl)-cytosin, Ara-C, Arabinocytidin, Arabinosylcytosin, Cytarabin, Cytosinarabinosid
• Empirische Formel (Hill-System): C₉H₁₃N₃O₅
• CAS-Nummer: 147-94-4
• Molekulargewicht: 243.22
• Beilstein: 89175
• MDL-Nummer: MFCD00066487
• UNSPSC-Code: 41116107
• NACRES: NA.24

Eigenschaften

• Qualität: pharmaceutical primary standard
• API-Familie: cytarabine
• Form: crystalline
• Haltbarkeit: limited shelf life, expiry date on the label
• Hersteller/Markenname: BP
• Anwendung(en): pharmaceutical; pharmaceutical small molecule
• Format: neat
• Lagertemp.: 2-8°C
• SMILES String: NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O
• InChI: 1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1
• InChIKey: UHDGCWIWMRVCDJ-CCXZUQQUSA-N
• Angaben zum Gen: human ... POLA1(5422) , POLA2(23649) , POLD1(5424) , POLD2(5425) , POLD3(10714) , POLD4(57804) , POLE(5426) , POLE2(5427) , POLE3(54107) , PRIM1(5557) , PRIM2(5558)

Beschreibung

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Cytarabine BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Cytarabine Injection

Biochem./physiol. Wirkung

Ara-C wird in DNA eingebaut und hemmt die DNA-Replikation durch Bildung von Spaltkomplexen mit Topoisomerase I, was zu einer Fragmentierung der DNA führt; die RNA-Synthese wird nicht gehemmt. Anti-Leukämiemittel.

Verpackung

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Sonstige Hinweise

Sales restrictions may apply.

Sicherheitshinweise

• Piktogramme: GHS08,GHS07
• Signalwort: Warning
• H-Sätze: H317,H361fd
• P-Sätze: P202 - P261 - P272 - P280 - P302 + P352 - P308 + P313
• Gefahreneinstufungen: Repr. 2 - Skin Sens. 1
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable