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B2635

Supelco

1,4-Butandiol-dimethansulfonat

analytical standard, for drug analysis

Synonym(e):

Busulfan

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About This Item

Lineare Formel:
CH3SO2O(CH2)4OSO2CH3
CAS-Nummer:
55-98-1
Molekulargewicht:
246.30
Beilstein:
1791786
EG-Nummer:
200-250-2
MDL-Nummer:
MFCD00007562
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329773205
NACRES:
NA.24

Qualität

analytical standard, for drug analysis

Qualitätsniveau

100

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

mp (Schmelzpunkt)

114-117 °C (lit.)

Anwendung(en)

forensics and toxicology
veterinary

Format

neat

SMILES String

CS(=O)(=O)OCCCCOS(C)(=O)=O

InChI

1S/C6H14O6S2/c1-13(7,8)11-5-3-4-6-12-14(2,9)10/h3-6H2,1-2H3

InChIKey

COVZYZSDYWQREU-UHFFFAOYSA-N

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Allgemeine Beschreibung

Busulfan is a bifunctional alkylating agent, which may find application in the treatment of chronic granulocytic leukemia.

Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Piktogramme

Skull and crossbonesHealth hazard
GHS06,GHS08

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Oral - Carc. 1A - Muta. 1B - Repr. 1B

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number
WXBF3873V
BCCK8828
BCCG5556
BCCF4469
BCCC6140

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Cyclophosphamid British Pharmacopoeia (BP) Reference Standard

BP1094

Cyclophosphamid

Ifosfamid ≥98%

Sigma-Aldrich

I4909

Ifosfamid

Cyclophosphamide Monohydrate A widely used anti-neoplastic agent that also displays immunosuppressant properties.

Sigma-Aldrich

239785

Cyclophosphamide Monohydrate

Poly(ethylenglykol) average mol wt 400

Sigma-Aldrich

P3265

Poly(ethylenglykol)

Blood and Marrow Stem Cell Transplantation: Principles, Practice, and Nursing Insights (1997)
Arnon Nagler et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(28), 3549-3556 (2013-08-28)
Cyclophosphamide (Cy) combined with total-body irradiation (TBI) or with busulfan (Bu) are currently the most common myeloablative regimens used in allogeneic stem-cell transplantation (alloSCT) in adults with acute myelogenous leukemia (AML). Intravenous (IV) Bu has more predictable bioavailability and a
Christopher Bredeson et al.
Blood, 122(24), 3871-3878 (2013-10-02)
We conducted a prospective cohort study testing the noninferiority of survival of ablative intravenous busulfan (IV-BU) vs ablative total body irradiation (TBI)-based regimens in myeloid malignancies. A total of 1483 patients undergoing transplantation for myeloid malignancies (IV-BU, N = 1025;
Manabu Ozawa et al.
Biology of reproduction, 94(4), 92-92 (2016-03-18)
The F-box and leucine-rich repeat protein 10 (Fbxl10) gene encodes a protein that catalyzes demethylation of H3K4 and H3K36. In this study, we show the important roles of FBXL10 as a histone demethylase in sustainable sperm production using mice in
Edward A Copelan et al.
Blood, 122(24), 3863-3870 (2013-09-26)
Cyclophosphamide combined with total body irradiation (Cy/TBI) or busulfan (BuCy) are the most widely used myeloablative conditioning regimens for allotransplants. Recent data regarding their comparative effectiveness are lacking. We analyzed data from the Center for International Blood and Marrow Transplant
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