860490P

Sphingosine (d18:1)

Avanti Research^™ - A Croda Brand

• Synonym(e): D-erythro-sphingosine
• Empirische Formel (Hill-System): C₁₈H₃₇NO₂
• CAS-Nummer: 123-78-4
• Molekulargewicht: 299.49
• UNSPSC-Code: 12352211
• NACRES: NA.25

Eigenschaften

• Form: powder
• Verpackung: pkg of 1 × 10 mg (860490P-10mg); pkg of 1 × 25 mg (860490P-25mg); pkg of 1 × 500 mg (860490P-500mg)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand
• Lipid-Typ: sphingolipids
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: OC[C@@](N)([H])[C@]([H])(O)/C=C/CCCCCCCCCCCCC
• InChI: 1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h14-15,17-18,20-21H,2-13,16,19H2,1H3/b15-14+/t17-,18+/m0/s1
• InChIKey: WWUZIQQURGPMPG-KRWOKUGFSA-N

Beschreibung

Allgemeine Beschreibung

Sphingosine (d18:1) is a spingoid base present in plant and animals. It has 2-amino-1,3-diol functionality and its extraction from animal tissue is laborious. Sphingosine (d18:1) synthesis is performed by chirospecific method using D-galactose.

Anwendung

Sphingosine (d18:1) has been used:

• for sphingosine inhalations studies in mice to evaluate its therapeutic potential in respiratory epithelial cells
• to investigate its effect on Pseudomonas aeruginosa strains
• as a standard in liquid chromatography tandem mass spectrophotometry for the quantification of epidermal ceramides

Biochem./physiol. Wirkung

Sphingosine (d18:1) is essential for physiological processes including cell differentiation, growth and survival. It activates the transient receptor potential cation channel subfamily member 3 (TRPM3).

Verpackung

20 mL Clear Glass Screw Cap Vial (860490P-500mg)

5 mL Amber Glass Screw Cap Vial (860490P-10mg)

5 mL Amber Glass Screw Cap Vial (860490P-25mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• H-Sätze: H413
• P-Sätze: P273 - P501
• Gefahreneinstufungen: Aquatic Chronic 4
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable