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Dokumente

C106402

Sigma-Aldrich

N-Cyclohexyl-N′-(2-Morpholinoethyl)carbodiimid-methyl-p-Toluolsulfonat

95%

Synonym(e):

4-[2-[(Cyclohexylcarbonimidoyl)-amino]-ethyl]-4-methylmorpholinium p-toluolsulfonat, N-Cyclohexyl-N′-(β-[N-methylmorpholino]-ethyl)-carbodiimid -p-toluolsulfonat (Salz), CMC, CMC metho-p-toluolsulfonat, Morpho CDI

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About This Item

Empirische Formel (Hill-System):
C14H26N3O · C7H7O3S
CAS-Nummer:
2491-17-0
Molekulargewicht:
423.57
EG-Nummer:
219-650-3
MDL-Nummer:
MFCD00011979
UNSPSC-Code:
12352111
PubChem Substanz-ID:
329774842
NACRES:
NA.26

Assay

95%

Form

crystals

mp (Schmelzpunkt)

113-115 °C (lit.)

SMILES String

Cc1ccc(cc1)S([O-])(=O)=O.C[N+]2(CCOCC2)CCN=C=NC3CCCCC3

InChI

1S/C14H26N3O.C7H8O3S/c1-17(9-11-18-12-10-17)8-7-15-13-16-14-5-3-2-4-6-14;1-6-2-4-7(5-3-6)11(8,9)10/h14H,2-12H2,1H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1

InChIKey

GBCAVSYHPPARHX-UHFFFAOYSA-M

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Anwendung

Employed in a facile sequencing technique for pseudouridylate residues in RNA.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

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A Bakin et al.
Biochemistry, 32(37), 9754-9762 (1993-09-21)
A new technique has been developed for the facile location of pseudouridylate (psi) residues in any RNA molecule. The method uses two known modification procedures which in combination uniquely identify U residues which have been converted into psi. The first
Carola Schafer et al.
Malaria journal, 17(1), 370-370 (2018-10-20)
Plasmodium vivax is the most geographically widespread of the human malaria parasites, causing 50,000 to 100,000 deaths annually. Plasmodium vivax parasites have the unique feature of forming dormant liver stages (hypnozoites) that can reactivate weeks or months after a parasite-infected
Jinghui Song et al.
Nature chemical biology, 16(2), 160-169 (2019-12-11)
Pseudouridine synthases (PUSs) are responsible for installation of pseudouridine (Ψ) modification in RNA. However, the activity and function of the PUS enzymes remain largely unexplored. Here we focus on human PUS10 and find that it co-expresses with the microprocessor (DROSHA-DGCR8
Cheng Deng et al.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 31(1), 88-93 (2011-02-22)
The purpose of this study was to fabricate decelluarized valve scaffold modified with polyethylene glycol nanoparticles loaded with transforming growth factor-β1 (TGF-β1), by which to improve the extracellular matrix microenvironment for heart valve tissue engineering in vitro. Polyethylene glycol nanoparticles
W A Ziehler et al.
Current protocols in nucleic acid chemistry, Chapter 6, Unit 6-Unit 6 (2008-04-23)
This unit provides thorough coverage of the most useful chemical and enzyme probes that can be used to examine RNA secondary and tertiary structure. Footprinting methods are presented using dimethyl sulfate, diethyl pyrocarbonate, ethylnitrosourea, kethoxal, CMCT, and nucleases. For chemical
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