779776

Methyl-β-Cyclodextrin

Wacker Chemie AG, ≥95.0% cyclodextrin basis (calculated)

• Synonym(e): Cavasol^® W7 M
• CAS-Nummer: 128446-36-6
• MDL-Nummer: MFCD00066764
• UNSPSC-Code: 12352201
• NACRES: NA.22

Eigenschaften

• Assay: ≥95.0% cyclodextrin basis (calculated)
• Form: powder
• Hersteller/Markenname: Wacker Chemie AG
• Kennzeichnungsgrad: 1.6-1.9 molar substitution
• Verunreinigungen: ≤0.2% unsubstituted cyclodextrin; ≤0.2% volatile organics; ≤2% chloride
• Verlust: ≤7.0% loss on drying
• mp (Schmelzpunkt): 180-182 °C (lit.)
• SMILES String: O1C2OC(C(OC3OC(C(OC4OC(C(OC5OC(C(OC6OC(C(OC7OC(C(OC8OC(C1C(C8OC)O)COC)C(C7OC)O)COC)C(C6OC)O)COC)C(C5OC)O)COC)C(C4OC)O)COC)C(C3OC)O)COC)C(C2OC)O)COC
• InChI: 1S/C56H98O35/c1-64-15-22-36-29(57)43(71-8)50(78-22)86-37-23(16-65-2)80-52(45(73-10)30(37)58)88-39-25(18-67-4)82-54(47(75-12)32(39)60)90-41-27(20-69-6)84-56(49(77-14)34(41)62)91-42-28(21-70-7)83-55(48(76-13)35(42)63)89-40-26(19-68-5)81-53(46(74-11)33(40)61)87-38-24(17-66-3)79-51(85-36)44(72-9)31(38)59/h22-63H,15-21H2,1-14H3
• InChIKey: QGKBSGBYSPTPKJ-UHFFFAOYSA-N

Beschreibung

Anwendung

Methyl-β-cyclodextrin (M-β-CD) can be used as a reactant to prepare ternary inclusion complex of diclofenac (DCF) in the presence of monoethanolamine (MEA). This complex improves the percutaneous absorption of DCF in human skin.[1] It can also be used to form an inclusion complex with olanzapine (OLP) to increase its solubility for efficient drug delivery.[2]

Sonstige Hinweise

For R&D Use

Rechtliche Hinweise

Cavasol is a registered trademark of Wacker Chemie AG

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): 368.6 °F
• Flammpunkt (°C): 187 °C