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Merck

C4805

Sigma-Aldrich

β-Cyclodextrin

powder, BioReagent, suitable for cell culture, ≥97%

Synonym(e):

Caraway, Cycloheptaamylose, Cyclomaltoheptaose, Schardingerβ-Dextrin

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About This Item

Empirische Formel (Hill-System):
C42H70O35
CAS-Nummer:
Molekulargewicht:
1134.98
Beilstein:
78623
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352201
PubChem Substanz-ID:
NACRES:
NA.77

Sterilität

non-sterile

Qualitätsniveau

Produktlinie

BioReagent

Assay

≥97%

Form

powder

Optische Aktivität

[α]20/D +162±3°, c = 1.5% in H2O

Methode(n)

cell culture | mammalian: suitable

mp (Schmelzpunkt)

290-300 °C (dec.) (lit.)

Löslichkeit

1 M NaOH: 50 mg/mL

Versandbedingung

ambient

Lagertemp.

room temp

SMILES String

OC[C@H]1O[C@@H]2O[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@@H]3CO)O[C@H]4[C@H](O)[C@@H](O)[C@H](O[C@@H]4CO)O[C@H]5[C@H](O)[C@@H](O)[C@H](O[C@@H]5CO)O[C@H]6[C@H](O)[C@@H](O)[C@H](O[C@@H]6CO)O[C@H]7[C@H](O)[C@@H](O)[C@H](O[C@@H]7CO)O[C@H]8[C@H](O)[C@@H](O)[C@H](O[C@@H]8CO)O[C@H]1[C@H](O)[C@H]2O

InChI

1S/C42H70O35/c43-1-8-29-15(50)22(57)36(64-8)72-30-9(2-44)66-38(24(59)17(30)52)74-32-11(4-46)68-40(26(61)19(32)54)76-34-13(6-48)70-42(28(63)21(34)56)77-35-14(7-49)69-41(27(62)20(35)55)75-33-12(5-47)67-39(25(60)18(33)53)73-31-10(3-45)65-37(71-29)23(58)16(31)51/h8-63H,1-7H2/t8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-/m1/s1

InChIKey

WHGYBXFWUBPSRW-FOUAGVGXSA-N

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Verwandte Kategorien

Anwendung

β-Cyclodextrin(β-CD) has been used in the synthesis of mono-6-tosyl-CD. It has also been used as a constituent in the serum-free medium to assess the involvement of cholesterol-dependent mechanisms in the uptake of nanoparticles by rat basophilic leukemia cells.

Biochem./physiol. Wirkung

β-Cyclodextrin is the cyclic α heptamer of glucose. It acts as a host to form inclusion compounds with the guests including derivatives of benzene, cyclohexane, adamantane, other alicyclic guests, and also inorganic molecules or ions. It is generally used to solubilize non-polar compounds such a fatty acids, lipids and cholesterol.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Labeling and exocytosis of secretory compartments in RBL mastocytes by polystyrene and mesoporous silica nanoparticles
Ekkapongpisit M, et al.
International journal of nanomedicine, 7, 1829-1829 (2012)
Space filling of beta-cyclodextrin and beta-cyclodextrin derivatives by volatile hydrophobic guests
Fourmentin S, et al.
Beilstein Journal of Organic Chemistry, 9(1), 1185-1191 (2013)
Synthesis of mono-6-tosyl-beta-cyclodextrin, a key intermediate for the functional cyclodextrin derivatives
Tan T, et al.
Protocol Exchange (2011)
Hanane Messiad et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 926, 21-27 (2013-03-30)
Piceatannol is one of resveratrol derivatives having health promoting potential. However, its low water-solubility and bioavailability could limit its use in both food and pharmaceutical fields. The aim of this work is the study of piceatannol complexation by β-cyclodextrin (β-CD)
Shuye Wang et al.
Journal of chromatography. A, 1277, 84-92 (2013-01-12)
Methoxyethylamine monosubstituted β-cyclodextrin, mono-6(A)-(2-methoxyethyl-1-ammonium)-6(A)-β-cyclodextrin chloride (MEtAMCD), is synthesized and analytically characterized. Bearing a methoxy group in cyclodextrin rim, MEtAMCD exhibits outstanding enantioselectivities toward ampholytic and acidic racemates in capillary electrophoresis. Driven by inclusion complexation, electrostatic interactions and/or hydrogen bonding, the

Artikel

How palmitic acid, other fatty acids and other cell culture components affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies.

Cyclodextrin solubilizes fat-soluble vitamins and hormones, enhancing their solubility in water for cell culture applications.

How the unsaturated fatty acid, oleic acid and other cell culture components affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies.

Techniques for solubilizing metabolically important compounds in aqueous solutions are reviewed.

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