253189

Tris-(diethylamido)-phosphin

97%

• Synonym(e): Hexaethyl-phosphorigsäure-triamid
• Lineare Formel: P[N(C₂H₅)₂]₃
• CAS-Nummer: 2283-11-6
• Molekulargewicht: 247.36
• Beilstein: 636187
• EG-Nummer: 218-920-8
• MDL-Nummer: MFCD00009041
• UNSPSC-Code: 12352001
• PubChem Substanz-ID: 24855300
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 200
• Assay: 97%
• Form: liquid
• Eignung der Reaktion: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand
• Brechungsindex: n20/D 1.475 (lit.)
• bp: 80-90 °C/10 mmHg (lit.)
• Dichte: 0.903 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: phosphine
• SMILES String: CCN(CC)P(N(CC)CC)N(CC)CC
• InChI: 1S/C12H30N3P/c1-7-13(8-2)16(14(9-3)10-4)15(11-5)12-6/h7-12H2,1-6H3
• InChIKey: FDIOSTIIZGWENY-UHFFFAOYSA-N

Beschreibung

Anwendung

Tris(diethylamino)phosphine [(Et₂N)₃P] can be used as a reagent to synthesize:

• 1,1′-Dialkylisoindigo derivatives by reacting with various 1-alkylisatins via deoxygenation reaction.[1]
• 1-Aminomethylisatins by treating with isatin and primary and secondary amines.[2]

It can also be used in the deoxygenation of some cyclic α-diketones using fullerene C₆₀.[3]

Sicherheitshinweise

• Piktogramme: GHS02,GHS07
• Signalwort: Warning
• H-Sätze: H226,H315,H319,H335
• P-Sätze: P210 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): 138.2 °F - closed cup
• Flammpunkt (°C): 59 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type ABEK (EN14387) respirator filter