T8657

Trichloroacetic acid

suitable for electrophoresis, suitable for fixing solution (for IEF and PAGE gels), ≥99%

• Synonyma: TCA
• Lineární vzorec: Cl₃CCOOH
• Číslo CAS: 76-03-9
• Molekulová hmotnost: 163.39
• Beilstein/REAXYS Number: 970119
• EC Number: 200-927-2
• MDL number: MFCD00004177
• UNSPSC Code: 41105319
• PubChem Substance ID: 24900550
• NACRES: NB.22

Vlastnosti

• vapor density: <1 (vs air)
• Quality Level: 200
• vapor pressure: 1 mmHg ( 51 °C)
• assay: ≥99%
• form: powder or flakes (or crystals)
• technique(s): electrophoresis: suitable
• turbidity: ≤3 NTU (1 g/ml)
• refractive index: n20/D 1.62 (lit.)
• bp: 196 °C (lit.)
• mp: 54-58 °C (lit.)
• solubility: water: 1 g/mL, clear, colorless
• density: 1.62 g/mL at 25 °C (lit.)
• anion traces: chloride (Cl^-): ≤0.001%; nitrate (NO₃^-): ≤0.002%; phosphate (PO₄^3-): ≤5 ppm; sulfate (SO₄^2-): ≤0.02%
• cation traces: Fe: ≤0.0005%; heavy metals (as Pb): ≤0.002%
• suitability: suitable for fixing solution (for IEF and PAGE gels)
• application(s): cell analysis
• storage temp.: 2-8°C
• SMILES string: OC(=O)C(Cl)(Cl)Cl
• InChI: 1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)
• InChI key: YNJBWRMUSHSURL-UHFFFAOYSA-N

Popis

General description

Trichloroacetic acid (TCA) is produced during the chlorination of water comprising natural organic material. It is a novel reagent used in clinical laboratories for deproteinization of body fluids. In addition, TCA is also used in the treatment of genital warts and acne scars.

Application

Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

Trichloroacetic acid has been used:

• for hydrolysis of DNA isolated from the cell
• for precipitation of glutathione isolated from seminal plasma
• as a fixative in microscopy

Bezpečnostní informace

• pictograms: GHS05,GHS09
• signalword: Danger
• hcodes: H314,H410
• pcodes: P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A
• Storage Class: 8B - Non-combustible corrosive hazardous materials
• wgk_germany: WGK 2
• flash_point_f: >235.4 °F - closed cup
• flash_point_c: > 113 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges