SML1101

Nedocromil sodium

≥98% (HPLC)

• Synonyma: 9-Ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano[3,2-g]quinoline-2,8-dicarboxylic acid sodium salt, Nedocromil disodium salt
• Empirický vzorec (Hillův zápis): C₁₉H₁₅NO₇ · 2 Na
• Číslo CAS: 69049-74-7
• Molekulová hmotnost: 415.30
• UNSPSC Code: 12352200
• NACRES: NA.77

Vlastnosti

• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: , white to beige to brown
• solubility: H₂O: 20 mg/mL, clear
• storage temp.: 2-8°C
• InChI: 1S/C19H17NO7.2Na/c1-3-5-9-16-10(13(21)7-12(18(23)24)20(16)4-2)6-11-14(22)8-15(19(25)26)27-17(9)11;;/h6-8H,3-5H2,1-2H3,(H,23,24)(H,25,26);;/q;2*+1/p-2
• Inchi Key: JQEKDNLKIVGXAU-UHFFFAOYSA-L

Popis

Biochem/physiol Actions

Nedocromil is a mast cell stabilizer and anti-inflammatory and anti-allergic drug. Nedocromil inhibits the degranulation of mast cells, and prevents the activation of and mediator release from a variety of inflammatory cell types. Nedocromil inhibits release of histamine, leukotriene C4, and prostaglandin D2, but has no antihistamine, bronchodilator, or corticosteroid activity itself.

Nedocromil is considered to be more effective in treating asthma compared to a placebo.

Bezpečnostní informace

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable