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SML1073

Sigma-Aldrich

BIX

≥98% (HPLC)

Synonyma:

2-(3,4-Dihydroxyphenyl)-2-oxoethyl ester thiocyanic acid, BiP protein Inducer X

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About This Item

Empirický vzorec (Hillův zápis):
C9H7NO3S
Číslo CAS:
101714-41-4
Molekulová hmotnost:
209.22
MDL number:
MFCD22415334
UNSPSC Code:
12352200
PubChem Substance ID:
329825455
NACRES:
NA.77

Quality Level

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

SMILES string

OC1=C(O)C=C(C(CSC#N)=O)C=C1

InChI

1S/C9H7NO3S/c10-5-14-4-9(13)6-1-2-7(11)8(12)3-6/h1-3,11-12H,4H2

InChI key

SVFLBLCWKKQKDW-UHFFFAOYSA-N

Application

BIX has been used in cell viability assay.

Biochem/physiol Actions

BIX (BiP protein inducer X) induces the expression of the endoplasmic reticulum chaperone protein GRP78 (glucose regulated protein 78, BiP) leading to an attenuation of the unfolded protein response. BIX protects neuronal cells and retinal cells from ER-stress induced cell death.
BIX is an inducer of molecular chaperone GRP78 (BIP, Glucose regulated protein 78).

Other Notes

air sensitive

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317

Hazard Classifications

Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Vyberte jednu z posledních verzí:

Osvědčení o analýze (COA)

Lot/Batch Number
0000435753
0000435751
0000435751
0000435753
0000423942

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