L9650

Lithium chloride

for molecular biology, ≥99%

• Synonyma: LiCl
• Lineární vzorec: LiCl
• Číslo CAS: 7447-41-8
• Molekulová hmotnost: 42.39
• EC Number: 231-212-3
• MDL number: MFCD00011078
• UNSPSC Code: 12352302
• PubChem Substance ID: 24896459
• NACRES: NA.31
• assay: ≥99%
• grade: for molecular biology
• form: powder
• solubility: H₂O: 100 mg/mL at 20 °C, clear, colorless

Vlastnosti

• grade: for molecular biology
• Quality Level: 200
• assay: ≥99%
• form: powder
• mp: 605 °C (lit.)
• solubility: H₂O: 100 mg/mL at 20 °C, clear, colorless
• anion traces: sulfate (SO₄^2-): ≤0.01%
• cation traces: Ba: ≤0.003%; Fe: ≤0.001%; K: ≤0.01%; Na: ≤0.20%; heavy metals (as Pb): ≤0.002%
• foreign activity: DNase, NICKase, RNase, protease, none detected
• SMILES string: [Li+].[Cl-]
• InChI: 1S/ClH.Li/h1H;/q;+1/p-1
• InChI key: KWGKDLIKAYFUFQ-UHFFFAOYSA-M

Popis

Application

Lithium chloride has been used:

• in the preparation of wash buffer for chromatin immunoprecipitation
• in 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay
• to treat aged myoblast as glycogen synthase kinase (GSK) inhibitor to analyse its effect on wingless/tailess (wnt) signaling

May be used to selectively pre­cipitate RNA.

Biochem/physiol Actions

Lithium chloride has the ability to block glycogen synthase kinase (GSK). It may also possess anti-inflammatory effects at low and non-toxic concentrations.

Bezpečnostní informace

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H315,H319
• pcodes: P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves