H4126

Hydrocortisone 21-acetate

≥98% (HPLC)

• Synonyma: 11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 21-acetate, 17-α-Hydroxycorticosterone acetate, 17-Hydroxycorticosterone 21-acetate, 21-Acetoxy-4-pregnene-11β,17α-diol-3,20-dione, 4-Pregnene-11β,17α,21-triol-3,20-dione 21-acetate
• Empirický vzorec (Hillův zápis): C₂₃H₃₂O₆
• Číslo CAS: 50-03-3
• Molekulová hmotnost: 404.50
• Beilstein/REAXYS Number: 2066841
• EC Number: 200-004-4
• MDL number: MFCD00037714
• UNSPSC Code: 12352200
• PubChem Substance ID: 24895620
• NACRES: NA.77

Vlastnosti

• sterility: non-sterile
• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• technique(s): permeability assay: suitable
• mp: 223 °C (dec.) (lit.)
• shipped in: ambient
• storage temp.: room temp
• SMILES string: [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)COC(C)=O
• InChI: 1S/C23H32O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-18,20,26,28H,4-9,11-12H2,1-3H3/t16-,17-,18-,20+,21-,22-,23-/m0/s1
• InChI key: ALEXXDVDDISNDU-JZYPGELDSA-N
• Gene Information: human ... NR3C1(2908) , SERPINA6(866)

Popis

General description

Hydrocortisone 21-acetate is an adrenocortical steroid. Hydrocortisone acts as an immunosuppressive drug and might suppress systemic inflammatory responses. It is used to treat rheumatoid arthritis and adrenal insufficiency. It also functions as an antiallergic agent.

Bezpečnostní informace

• pictograms: GHS08
• signalword: Danger
• hcodes: H360Df,H373
• pcodes: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 1B - STOT RE 2
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves