D6000

2′-Deoxyadenosine 5′-di­phos­phate sodium salt

• Synonyma: dADP
• Empirický vzorec (Hillův zápis): C₁₀H₁₅N₅O₉P₂ · xNa⁺
• Číslo CAS: 72003-83-9
• Molekulová hmotnost: 411.20 (free acid basis)
• EC Number: 276-280-5
• MDL number: MFCD00083610
• UNSPSC Code: 41106305
• PubChem Substance ID: 24893990
• NACRES: NA.51

Vlastnosti

• biological source: synthetic (organic)
• Quality Level: 200
• assay: ≥95% (HPLC)
• form: powder
• storage temp.: −20°C
• SMILES string: [Na].Nc1ncnc2n(cnc12)C3CC(O)C(COP(O)(=O)OP(O)(O)=O)O3
• InChI: 1S/C10H15N5O9P2.Na.H/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(23-7)2-22-26(20,21)24-25(17,18)19;;/h3-7,16H,1-2H2,(H,20,21)(H2,11,12,13)(H2,17,18,19);;
• InChI key: KZGAPWRJMWSNQO-UHFFFAOYSA-N

Popis

General description

2′-Deoxyadenosine5′-di­phos­phate (dADP) is a purine containing adenine as the nucleobase. It isproduced as a product of hypoxanthine oxidase action on hypoxanthine duringpurine degradation in the body.

Application

2′-Deoxyadenosine 5′-diphosphate (dADP) may be used for the synthesis of deoxyadenylate oligonucleotides with enzymes such as polynucleotide phosphorylase from Escherichia coli. dADP is used as an inhibitor of bacterial poly(A) polymerase. DeoxyADP may be use as an alternative substrate or inhibitor for studies of ATPase and DNA and RNA polymerase specificity.

Bezpečnostní informace

• pictograms: GHS06
• signalword: Danger
• hcodes: H301 + H311 + H331,H315,H319,H335
• pcodes: P261 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges