D1156
N,N-Dimethylglycine
≥99%, suitable for ligand binding assays
Synonyma:
(Dimethylamino)acetic acid
Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen
About This Item
Lineární vzorec:
(CH3)2NCH2COOH
Číslo CAS:
Molekulová hmotnost:
103.12
Beilstein/REAXYS Number:
1700261
EC Number:
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26
Doporučené produkty
Název produktu
N,N-Dimethylglycine, ≥99%
Quality Level
assay
≥99%
form
powder
technique(s)
ligand binding assay: suitable
color
white to off-white
mp
178-182 °C (lit.)
application(s)
peptide synthesis
SMILES string
CN(C)CC(O)=O
InChI
1S/C4H9NO2/c1-5(2)3-4(6)7/h3H2,1-2H3,(H,6,7)
InChI key
FFDGPVCHZBVARC-UHFFFAOYSA-N
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Biochem/physiol Actions
N,N-Dimethylglycine (DMG) is a natural N-methylated glycine that is used in comparative analysis with other N-methylated glycines such as sarcosine and βine. N,N-Dimethylglycine is used in the development of glycine-based ionic liquids and emulsifiers. N,N-Dimethylglycine is potentially useful as a biomarker of protein degradation in COPD patients. DMG is used as a substrate to identify, differentiate and characterize amino acid methyltransferase(s).
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Baljit K Ubhi et al.
The European respiratory journal, 40(2), 345-355 (2011-12-21)
There is a paucity of biomarkers for chronic obstructive pulmonary disease (COPD). Metabolomics were applied to a defined COPD patient cohort from the ECLIPSE study (Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points). Results were correlated with accepted biomarkers
S H Moolenaar et al.
Clinical chemistry, 45(4), 459-464 (1999-04-02)
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B A Binzak et al.
American journal of human genetics, 68(4), 839-847 (2001-03-07)
Dimethylglycine dehydrogenase (DMGDH) (E.C. number 1.5.99.2) is a mitochondrial matrix enzyme involved in the metabolism of choline, converting dimethylglycine to sarcosine. Sarcosine is then transformed to glycine by sarcosine dehydrogenase (E.C. number 1.5.99.1). Both enzymes use flavin adenine dinucleotide and
Ali A Moazzami et al.
The Journal of nutrition, 141(12), 2126-2132 (2011-10-21)
Prostate cancer (PC) is the most common cancer in the Western world and the second most important cancer causing male deaths, after lung cancer, in the United States and Britain. Lifestyle and dietary changes are recommended for men diagnosed with
Isabelle D Kalmar et al.
The British journal of nutrition, 107(11), 1635-1644 (2011-09-21)
N,N-Dimethylglycine (DMG) is a tertiary amino acid that naturally occurs as an intermediate metabolite in choline-to-glycine metabolism. The objective of the present trial was to evaluate tolerance, safety and bioaccumulation of dietary DMG in broilers when supplemented at 1 g
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