Human albumin has a molecular weight of approximately 67 kDa.
A9511
Albumin from human serum
lyophilized powder, ≥97% (agarose gel electrophoresis)
Synonyma:
HSA
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Vybrat velikost
100 MG
1 540,00 Kč
500 MG
4 140,00 Kč
1 G
6 480,00 Kč
5 G
23 500,00 Kč
10 G
28 400,00 Kč
25 G
59 600,00 Kč
1 540,00 Kč
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O této položce
Číslo CAS:
UNSPSC Code:
12352202
eCl@ss:
42010201
EC Number:
274-272-6
NACRES:
NA.25
MDL number:
Biological source:
human
Assay:
≥97% (agarose gel electrophoresis)
Form:
lyophilized powder
Technique(s):
ELISA: suitable
tissue culture: suitable
western blot: suitable
tissue culture: suitable
western blot: suitable
Impurities:
HIV I and HIVII, HCV and HBsAg, tested negative
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Dovolte nám, abychom vám pomohliNázev produktu
Albumin from human serum, lyophilized powder, ≥97% (agarose gel electrophoresis)
SMILES string
FC(F)(F)C(F)(F)C(F)(F)F
InChI
1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
InChI key
QYSGYZVSCZSLHT-UHFFFAOYSA-N
biological source
human
assay
≥97% (agarose gel electrophoresis)
form
lyophilized powder
mol wt
monomer calculated mol wt 66478 Da
technique(s)
ELISA: suitable
tissue culture: suitable
western blot: suitable
impurities
HIV I and HIVII, HCV and HBsAg, tested negative
solubility
H2O: soluble 50 mg/mL
UniProt accession no.
storage temp.
2-8°C
Quality Level
Gene Information
human ... ALB(213)
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Tato položka | A8301 | 126654 | A7736 |
|---|---|---|---|
| assay ≥97% (agarose gel electrophoresis) | assay 90-100% protein basis (biuret) | assay ≥95% (SDS-PAGE) | assay ≥90% (agarose gel electrophoresis) |
| biological source human | biological source human | biological source - | biological source human |
| technique(s) ELISA: suitable, western blot: suitable, tissue culture: suitable | technique(s) cell culture | mammalian: suitable | technique(s) protein quantification: suitable | technique(s) cell culture | mammalian: suitable |
| Quality Level 300 | Quality Level 200 | Quality Level - | Quality Level 300 |
| form lyophilized powder | form lyophilized powder | form lyophilized solid (Salt-free) | form lyophilized powder |
| impurities HIV I and HIVII, HCV and HBsAg, tested negative | impurities - | impurities - | impurities - |
Application
Albumin from human serum has been used:
- to standardize the column for molecular-exclusion chromatography[1]
- to prepare the tobacco mosaic virus (TMV)-poly ethylene glycol (PEG8)-serum albumin (SA) particles[2]
- to analyze its modifications after oxidation using a Fenton system[3]
Albumin-bound fluorescence was used in serum of patients with chronic renal failure.[1]
Biochem/physiol Actions
Albumin turnover is seen in infants with iron deficiency anemia.[4] Serum albumin is a reliable prognostic indicator in liver disease. Oxidative modification of albumin is seen in advanced liver disease.[5]
Albumins are soluble monomeric proteins found in the body fluids and tissues of animals and in some plant seeds. Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones. Serum albumins are also vital in regulating the colloidal osmotic pressures of blood.
Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones, and is vital in regulating the colloidal osmotic pressures of blood. Albumin is also seen to bind to exogenous substances, particularly drugs (e.g., ibuprofen, warfarin), and strongly influence their pharmacokinetics. Oxidative stress leading to changes in the redox state of albumin has widely varied effects on its physiological function.
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
General description
Albumin is the most copious protein in blood plasma. Liver produces human albumin. [6]
Human albumin possess a molecular weight of 67 kDa.[7]
Other Notes
View more information on human serum albumin.
Preparation Note
Prepared using method IV of Cohn, E.J., et al., J. Am. Chem. Soc., 69, 1753 (1947).
Skladovací třída
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
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Již tento produkt vlastníte?
Dokumenty související s produkty, které jste v minulosti zakoupili, byly za účelem usnadnění shromážděny ve vaší Knihovně dokumentů.
Elham Behzadi et al.
International journal of nanomedicine, 14, 257-270 (2019-01-16)
Recently, nanomaterials have moved into biological and medicinal implementations like cancer therapy. Therefore, before clinical trials, their binding to plasma proteins like human serum albumin (HSA) and their cytotoxic effects against normal and cancer cell lines should be addressed. Herein
Serum albumin camouflage of plant virus based nanoparticles prevents their antibody recognition and enhances pharmacokinetics
Pitek A, et al.
Biomaterials, 89(7-8), 89-97 (2016)
Effects of Fenton Reaction on Human Serum Albumin: An In Vitro Study
Khosravifarsani M, et al.
Electron Physician, 8(9), 2970-2970 (2016)
Oxidative damage of albumin in advanced liver disease
Oettl K, et al.
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, 1782, 469-473 (2008)
Daniele Sanna et al.
Inorganic chemistry, 49(1), 174-187 (2009-12-02)
The possible biotransformations in the blood serum of four representative insulin-enhancing vanadium compounds, [VO(6-mepic)(2)], cis-[VO(pic)(2)(H(2)O)], [VO(acac)(2)], and [VO(dhp)(2)], where 6-mepic, pic, acac, and dhp indicate the deprotonated forms of 6-methylpicolinic and picolinic acids, acetylacetone, and 1,2-dimethyl-3-hydroxy-4(1H)-pyridinone, were examined. In particular
Sortimentní položky
Explore serum albumin's role in serum-free cell culture systems for biomanufacturing.
Prozkoumejte úlohu sérového albuminu v systémech bezsérových buněčných kultur pro biomanufacturing.
Související obsah
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What is the molecular weight of this product?
1 answer-
Helpful?
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アルブミンの屈折率 情報ありますか？
1 answer-
This product is not tested for refractive index, however, the incremental refractive index is reported in the general Human Serum Albumin datasheet.
See page 2, PHYSICAL PROPERTIES, at the link below:
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/175/446/a9511pis.pdfHelpful?
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What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
Helpful?
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Can Product A9511, Human serum albumin (HSA), be used for cell culture applications?
1 answer-
Although A9511 is not sterile or endotoxin tested, it can probably still be used in cell culture. Filtering a solution of HSA through a 0.45 micron filter, then a 0.2 micron filter would provide a solution that is sterile, and likely suitable for cells. A5843 is an HSA product that has been endotoxin tested.
Helpful?
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What are the impurities for Product A9511, Human serum albumin (HSA)?
1 answer-
The impurities present are alpha-globulin and beta-globulin.
Helpful?
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