72715

Glutaryl-L-carnitine lithium salt

≥98.0% (TLC)

• Synonyma: L-Carnitine lithium glutarate
• Empirický vzorec (Hillův zápis): C₁₂H₂₁NO₆ · xLi⁺
• Číslo CAS: 102636-82-8
• Molekulová hmotnost: 275.30 (free acid basis)
• UNSPSC Code: 41116107
• PubChem Substance ID: 329764299
• NACRES: NA.25

Vlastnosti

• product name: Glutaryl-L-carnitine lithium salt, ≥98.0% (TLC)
• Quality Level: 100
• assay: ≥98.0% (TLC)
• form: solid
• optical activity: [α]/D -20±2°, c = 1 in H₂O
• impurities: ≤10% water
• color: white to off-white
• storage temp.: 2-8°C
• SMILES string: C[N+](C)(C)C[C@H](OC(CCCC(O)=O)=O)CC([O-])=O.C
• InChI: 1S/C12H21NO6/c1-13(2,3)8-9(7-11(16)17)19-12(18)6-4-5-10(14)15/h9H,4-8H2,1-3H3,(H-,14,15,16,17)/t9-/m1/s1
• InChI key: NXJAXUYOQLTISD-SECBINFHSA-N

Popis

Biochem/physiol Actions

Increased formation and excretion of glutarylcarnitin results from a glutaryl-CoA dehydrogenase deficiency, an inborn error of lysine and tryptophan metabolism. Secondary carnitine depletion due to increased formation and urinary excretion of glutarylcarnitine is suggested to play an important role in the neuropathogenesis of glutaryl-CoA dehydrogenase deficiency, inducing excitotoxic neuronal damage and mitochondrial dysfunction.

Bezpečnostní informace

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable