Přejít k obsahu
Merck
Všechny fotografie(1)

Key Documents

View All Documentation

Y0001445

Celecoxib

European Pharmacopoeia (EP) Reference Standard

Synonyma:

4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide, CJ-016377, CP-598107, PF-00345549, PHA-00846533, SC-58635, YM-177

Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen
Všechny fotografie(1)

About This Item

Empirický vzorec (Hillův zápis):
C17H14F3N3O2S
Číslo CAS:
169590-42-5
Molekulová hmotnost:
381.37
MDL number:
MFCD00941298
UNSPSC Code:
41116107
PubChem Substance ID:
329831427
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

celecoxib

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Cc1ccc(cc1)-c2cc(nn2-c3ccc(cc3)S(N)(=O)=O)C(F)(F)F

InChI

1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)

InChI key

RZEKVGVHFLEQIL-UHFFFAOYSA-N

Gene Information

human ... PTGS2(5743)

Hledáte podobné produkty? Navštivte Průvodce porovnáváním produktů

Související kategorie

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Celecoxib EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Celecoxib is a non-steroidal, anti-inflammatory drug (NSAID) and a cyclooxygenase-2 (COX-2) selective inhibitor. Celecoxib is at least 10-20 times more selective for COX-2 over COX-1.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Related product

Č. produktu
Popis
Stanovení ceny

Y0001446

Celecoxib impurity A, European Pharmacopoeia (EP) Reference Standard

Y0001447

Celecoxib impurity B, European Pharmacopoeia (EP) Reference Standard

PHR1683

Celecoxib, Pharmaceutical Secondary Standard; Certified Reference Material

1098515

Celecoxib Related Compound A, United States Pharmacopeia (USP) Reference Standard

1098526

Celecoxib Related Compound B, United States Pharmacopeia (USP) Reference Standard

1098504

Celecoxib, United States Pharmacopeia (USP) Reference Standard

1098537

Celecoxib Related Compound C, United States Pharmacopeia (USP) Reference Standard

1098570

Celecoxib Related Compound D, United States Pharmacopeia (USP) Reference Standard

BP1230

Celecoxib, British Pharmacopoeia (BP) Reference Standard

pictograms

Health hazardEnvironment
GHS08,GHS09

signalword

Danger

Hazard Classifications

Aquatic Chronic 1 - Repr. 1B - STOT RE 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Vyberte jednu z posledních verzí:

Osvědčení o analýze (COA)

Lot/Batch Number

Je nám líto, ale pro tento produkt momentálně nemáme COA k dispozici online.

Potřebujete-li pomoc, obraťte se na Zákaznická podpora

Již tento produkt vlastníte?

Dokumenty související s produkty, které jste v minulosti zakoupili, byly za účelem usnadnění shromážděny ve vaší Knihovně dokumentů.

Navštívit knihovnu dokumentů

Zákazníci si také prohlíželi

Slide 1 of 7

1 of 7

Daidzein ≥98%, synthetic

Sigma-Aldrich

D7802

Daidzein

Ketoprofen ≥98% (TLC)

Sigma-Aldrich

K1751

Ketoprofen

Pregabalin European Pharmacopoeia (EP) Reference Standard

Y0001805

Pregabalin

Aspirin meets USP testing specifications

Sigma-Aldrich

A2093

Aspirin

N-Nitrosodimethylamine (NDMA) solution certified reference material, 5000 μg/mL in methanol, ampule of 1 mL

Supelco

CRM40059

N-Nitrosodimethylamine (NDMA) solution

Ibuprofen Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1004

Ibuprofen

Ibuprofen ≥98% (GC)

Sigma-Aldrich

I4883

Ibuprofen

Verena Jendrossek
Cancer letters, 332(2), 313-324 (2011-02-25)
Celecoxib is a paradigmatic selective inhibitor of cyclooxygenase-2 (COX-2). This anti-inflammatory drug has potent anti-tumor activity in a wide variety of human epithelial tumor types, such as colorectal, breast, non-small cell lung, and prostate cancers. Up to now, the drug
Sheena Derry et al.
The Cochrane database of systematic reviews, 10(10), CD004233-CD004233 (2013-10-24)
This is an update of a review first published in The Cochrane Library in Issue 4, 2008, and updated in Issue 3, 2012. Celecoxib is a selective cyclo-oxygenase-2 (COX-2) inhibitor usually prescribed for the relief of chronic pain in osteoarthritis
Paul L McCormack
Drugs, 71(18), 2457-2489 (2011-12-07)
Celecoxib (Celebrex®) was the first cyclo-oxygenase (COX)-2 selective inhibitor (coxib) to be introduced into clinical practice. Coxibs were developed to provide anti-inflammatory/analgesic activity similar to that of nonselective NSAIDs, but without their upper gastrointestinal (GI) toxicity, which is thought to
Axel H Schönthal et al.
Expert opinion on investigational drugs, 17(2), 197-208 (2008-01-31)
Celecoxib is an NSAID that was developed as a selective inhibitor of COX-2 and approved by the FDA for the treatment of various forms of arthritis and the management of acute or chronic pain. In addition, it was more recently
Leyte L Winfield et al.
Future medicinal chemistry, 4(3), 361-383 (2012-03-08)
Celecoxib is a multifaceted drug with promising anticancer properties. A number of studies have been conducted that implicate the compound in modulating the expression of Bcl-2 family members and mitochondria-mediated apoptosis. The growing data surrounding the role of celecoxib in
Zobrazit všechny související dokumenty

Náš tým vědeckých pracovníků má zkušenosti ve všech oblastech výzkumu, včetně přírodních věd, materiálových věd, chemické syntézy, chromatografie, analytiky a mnoha dalších..

Obraťte se na technický servis.