PHR1908

Acetazolamide

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonyma: Acetazolamide, 5-Acetamido-1,3,4-thiadiazole-2-sulfonamide, N-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide, N-(5-[Aminosulfonyl]-1,3,4-thiadiazol-2-yl)acetamide
• Empirický vzorec (Hillův zápis): C₄H₆N₄O₃S₂
• Číslo CAS: 59-66-5
• Molekulová hmotnost: 222.25
• EC Number: 200-440-5
• MDL number: MFCD00003105
• UNSPSC Code: 41116107
• NACRES: NA.24

Vlastnosti

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• agency: traceable to BP 904; traceable to Ph. Eur. A0100000; traceable to USP 1005004
• API family: acetazolamide
• CofA: current certificate can be downloaded
• packaging: pkg of 5 g
• application(s): pharmaceutical
• format: neat
• storage temp.: 2-30°C
• SMILES string: CC(=O)Nc1nnc(s1)S(N)(=O)=O
• InChI: 1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
• InChI key: BZKPWHYZMXOIDC-UHFFFAOYSA-N
• Gene Information: human ... CA1(759) , CA12(771) , CA2(760) , CA4(762)

Popis

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Application

Carbonic anhydrase inhibitor; increases cerebral blood flow.

Biochem/physiol Actions

Inhibits water permeability of membranes by interacting with aquaporins

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB0911 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

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Bezpečnostní informace

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319
• pcodes: P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable