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Key Documents

A-020

Supelco

Amobarbital solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirický vzorec (Hillův zápis):
C11H18N2O3
Číslo CAS:
Molekulová hmotnost:
226.27
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material

Quality Level

form

liquid

feature

SNAP-N-SPIKE®. SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal)

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

SMILES string

O=C(NC(C1(CC)CCC(C)C)=O)NC1=O

InChI

1S/C11H18N2O3/c1-4-11(6-5-7(2)3)8(14)12-10(16)13-9(11)15/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16)

InChI key

VIROVYVQCGLCII-UHFFFAOYSA-N

General description

A Certified Spiking Solution® for amobarbital testing methods by GC/MS or LC/MS for clinical toxicology, medication monitoring, forensic analysis, pain prescription monitoring, or urine drug testing applications. Amobarbital is a barbiturate approved for treatment of anxiety, insomnia, and epilepsy.

Application



  • Barbiturate biochemical analysis: A study detailed a new approach for the analysis of barbiturates, including amobarbital, using ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS), highlighting advancements in detecting and quantifying these substances in forensic and toxicological contexts (Wachełko et al., 2023).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup


Osvědčení o analýze (COA)

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Impact of pretreatment with amobarbital on electroconvulsive therapy outcomes.
Clint Ross et al.
The journal of ECT, 29(1), e10-e11 (2013-02-21)
Daniel L Drane et al.
Epilepsia, 53(10), 1790-1798 (2012-07-12)
Exclusive right hemisphere language lateralization is rarely observed in the Wada angiography results of epilepsy surgery patients. Cortical stimulation mapping (CSM) is infrequently performed in such patients, as most undergo nondominant left hemisphere resections, which are presumed not to pose
Propofol, amobarbital… is it the substance that matters, or the question about the role of the Wada test in brain tumor patients?
Karl Schaller
World neurosurgery, 75(3-4), 428-430 (2011-05-24)
Kathrin Wagner et al.
Journal of neurology, neurosurgery, and psychiatry, 83(5), 503-509 (2012-03-08)
The Wada test has been the gold standard for testing cerebral language localisation during presurgical investigation in the past decades. However, during the last few years a shift has occurred in epilepsy surgery programmes towards the use of non-invasive methods
Julián Carvajal-Castrillón et al.
Revista de neurologia, 55(9), 520-527 (2012-11-01)
An appropriate localization of ictal onset zone in refractory temporal lobe epilepsy favors an adequate outcome associated with surgical treatment. When video-electroencephalogram (video-EEG) and magnetic resonance imaging do not provide accurate data to locate ictal onset zone, the use of

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