PHR1664

Rifamycin Sodium

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonyma: Rifamycin SV sodium salt
• Empirický vzorec (Hillův zápis): C₃₇H₄₆NNaO₁₂
• Číslo CAS: 14897-39-3
• Molekulová hmotnost: 719.75
• EC Number: 238-965-7
• UNSPSC Code: 41116107
• NACRES: NA.24

Vlastnosti

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• agency: traceable to Ph. Eur. R1000000
• API family: rifampicin, rifamycin
• CofA: current certificate can be downloaded
• packaging: pkg of 500 mg
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: -10 to -25°C
• SMILES string: [Na+].CO[C@H]1\C=C\O[C@@]2(C)Oc3c(C)c(O)c4c(O)c(NC(=O)C(C)=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)cc([O-])c4c3C2=O
• InChI: 1S/C37H47NO12.Na/c1-16-11-10-12-17(2)36(46)38-23-15-24(40)26-27(32(23)44)31(43)21(6)34-28(26)35(45)37(8,50-34)48-14-13-25(47-9)18(3)33(49-22(7)39)20(5)30(42)19(4)29(16)41;/h10-16,18-20,25,29-30,33,40-44H,1-9H3,(H,38,46);/q;+1/p-1/b11-10+,14-13+,17-12-;/t16-,18+,19+,20+,25-,29-,30+,33+,37-;/m0./s1
• InChI key: YVOFSHPIJOYKSH-NLYBMVFSSA-M

Popis

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Rifamycin Sodium is a simplest rifamycin obtained via the elimination of glycolic moity from rifamycin B. It belongs to the ansamicin group of antibiotics. Rifamycin sodium is widely used in surgery and for the treatment of synovitis by intracellular injections.

Application

Rifamycin Sodium may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using manual and semiautomatic kinetic method.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA6000 in the slot below. This is an example certificate only and may not be the lot that you receive.

Bezpečnostní informace

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable