PHR1448

Sulfadimethoxine

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonyma: Sulfadimethoxine, 4-Amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide
• Empirický vzorec (Hillův zápis): C₁₂H₁₄N₄O₄S
• Číslo CAS: 122-11-2
• Molekulová hmotnost: 310.33
• Beilstein/REAXYS Number: 306856
• EC Number: 204-523-7
• MDL number: MFCD00057345
• UNSPSC Code: 41116107
• PubChem Substance ID: 329822608
• NACRES: NA.24

Vlastnosti

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• agency: traceable to USP 1626001
• API family: sulfadimethoxine
• CofA: current certificate can be downloaded
• packaging: pkg of 500 mg
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-30°C
• SMILES string: COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1
• InChI: 1S/C12H14N4O4S/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)
• InChI key: ZZORFUFYDOWNEF-UHFFFAOYSA-N

Popis

General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Sulfadimethoxine is an long acting sulfonamide antibiotic, commonly used against a broad spectrum of bacterial infections in animals. Its mode of action involves the inhibition of folic acid synthesis in prokaryotes. It is also widely used in veterinary medication to treat coccidiosis in cats and dogs.

Application

Sulfadimethoxine may be used as a pharmaceutical reference standard for the quantification of the analyte in veterinary formulations using liquid chromatography technique.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA2825 in the slot below. This is an example certificate only and may not be the lot that you receive.

Bezpečnostní informace

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3