B1120000

Biperiden hydrochloride

European Pharmacopoeia (EP) Reference Standard

• Synonyma: 1-(5-Bicyclo[2.2.1]hept-2-enyl)-1-phenyl-3-(1-piperidinyl)propan-1-ol hydrochloride, Akineton, Akinophyl
• Empirický vzorec (Hillův zápis): C₂₁H₃₀ClNO
• Číslo CAS: 1235-82-1
• Molekulová hmotnost: 347.92
• MDL number: MFCD00797516
• UNSPSC Code: 41116107
• NACRES: NA.24

Vlastnosti

• grade: pharmaceutical primary standard
• API family: biperiden
• manufacturer/tradename: EDQM
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: Cl[H].OC(CCN1CCCCC1)(C2CC3CC2C=C3)c4ccccc4
• InChI: 1S/C21H29NO.ClH/c23-21(19-7-3-1-4-8-19,11-14-22-12-5-2-6-13-22)20-16-17-9-10-18(20)15-17;/h1,3-4,7-10,17-18,20,23H,2,5-6,11-16H2;1H
• InChI key: RDNLAULGBSQZMP-UHFFFAOYSA-N
• Gene Information: human ... CHRM1(1128)

Popis

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Biperiden hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Antiparkinsonian; non-selective muscarinic receptor antagonist.

Biperiden hydrochloride is antiparkinsonian; non-selective muscarinic receptor antagonist. It is used for the adjunctive treatment of all forms of Parkinson′s Disease (postencephalitic, idiopathic, and arteriosclerotic); also commonly used to improve parkinsonian signs and symptoms related to antipsychotic drug therapy. LD₅₀ in rats 750 mg/kg; in dogs 340 mg/kg.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Bezpečnostní informace

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable