90527

Hydroxychloroquine sulfate

analytical standard

• Synonyma: 7-Chloro-4-[4-(N-ethyl-N-b-hydroxyethylamino)-1-methylbutylamino]quinoline sulfate
• Empirický vzorec (Hillův zápis): C₁₈H₂₆ClN₃O · H₂SO₄
• Číslo CAS: 747-36-4
• Molekulová hmotnost: 433.95
• EC Number: 212-019-3
• MDL number: MFCD00078203
• UNSPSC Code: 41116107
• PubChem Substance ID: 329769919
• NACRES: NA.24

Vlastnosti

• grade: analytical standard
• Quality Level: 100
• assay: ≥95.0% (HPLC)
• shelf life: limited shelf life, expiry date on the label
• packaging: pkg of 50 mg
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• impurities: ≤1.0% water
• color: white to off-white
• application(s): forensics and toxicology; pharmaceutical (small molecule); veterinary
• format: neat
• storage temp.: 2-8°C
• SMILES string: OS(O)(=O)=O.CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12
• InChI: 1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)
• InChI key: JCBIVZZPXRZKTI-UHFFFAOYSA-N
• Gene Information: human ... TLR7(51284) , TLR9(54106)

Popis

General description

Hydroxychloroquine Sulfate (Hydroxychloroquine Sulphate) is a salt of hydroxychloroquine (HCQ, Plaquenil), a 4-aminoquinoline based antiviral drug.

Application

Hydroxychloroquine Sulfate can be used as an analytical standard for the determination of the analyte in pharmaceutical formulations, and biological samples by various analytical techniques.

Biochem/physiol Actions

Hydroxychloroquine sulfate is an anti-inflammatory (via TNF), disease-modifying antirheumatic drug (DMARD), and a heme polymerase inhibitor. It is used in treating malaria.

Bezpečnostní informace

• pictograms: GHS07
• signalword: Warning
• hcodes: H302 - H315 - H319
• pcodes: P264 - P270 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable