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54752

Sigma-Aldrich

Methyl 4-hydroxybenzoate

tested according to Ph. Eur.

Synonyma:

Methylis parahydroxybenzoas, p-Hydroxybenzoic acid methyl ester, Methyl paraben, NIPAGIN

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About This Item

Lineární vzorec:
HOC6H4CO2CH3
Číslo CAS:
99-76-3
Molekulová hmotnost:
152.15
Beilstein/REAXYS Number:
509801
EC Number:
202-785-7
MDL number:
MFCD00002352
UNSPSC Code:
51452201
PubChem Substance ID:
329758052
NACRES:
NA.25

agency

USP/NF
tested according to Ph. Eur.

assay

99.7%

form

solid

mp

125-128 °C (lit.)

application(s)

pharmaceutical (small molecule)

SMILES string

COC(=O)c1ccc(O)cc1

InChI

1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3

InChI key

LXCFILQKKLGQFO-UHFFFAOYSA-N

Gene Information

rat ... Ar(24208)

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Application


  • Single crystal, Hirshfeld surface and theoretical analysis of methyl 4-hydroxybenzoate, a common cosmetic, drug and food preservative-Experiment versus theory.: This research provides a detailed analysis of the crystal structure of Methyl 4-hydroxybenzoate, offering insights into its stability and effectiveness as a preservative in various applications, including cosmetics and pharmaceuticals (Sharfalddin et al., 2020).

  • Photostabilization of papaverine hydrochloride solutions.: This article explores the role of Methyl 4-hydroxybenzoate in enhancing the photostability of papaverine hydrochloride solutions, crucial for maintaining the efficacy of this pharmaceutical under exposure to light (Piotrowska et al., 2010).

pictograms

Environment
GHS09

hcodes

H411

Hazard Classifications

Aquatic Chronic 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

334.4 °F

flash_point_c

168 °C

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Osvědčení o analýze (COA)

Lot/Batch Number
BCCL6922
BCCK9188
BCCK3578
BCCJ8350
BCCH8766

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Propyl 4-hydroxybenzoate EMPROVE® EXPERT, Ph. Eur., BP, JP, NF

SAFC

1.07427

Propyl 4-hydroxybenzoate

Methyl Paraben PESTANAL®, analytical standard

Supelco

47889

Methyl Paraben

Methyl 4-hydroxybenzoate sodium salt tested according to Ph. Eur.

Sigma-Aldrich

85265

Methyl 4-hydroxybenzoate sodium salt

Methyl 4-hydroxybenzoate sodium salt EMPROVE® ESSENTIAL, Ph. Eur., BP, NF

SAFC

1.06756

Methyl 4-hydroxybenzoate sodium salt

Propyl 4-hydroxybenzoate ≥99%

Sigma-Aldrich

P53357

Propyl 4-hydroxybenzoate

Potassium sorbate granules, EMPROVE® ESSENTIAL, Ph. Eur., BP, NF, FCC, E 202

SAFC

1.05119

Potassium sorbate

Methylparaben Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1012

Methylparaben

Methylparaben certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Supelco

79721

Methylparaben

Ismail I Hewala et al.
Talanta, 88, 623-630 (2012-01-24)
Simple methods for HPTLC peak purity assessment and identification of the HPTLC peaks were presented. The spectrodensitograms - selected at different time intervals across the elution time of the HPTLC peak - were extracted and digital algorithms for manipulating the
Gabriela Oliveira et al.
International journal of pharmaceutics, 435(1), 38-49 (2012-05-29)
Simple topical formulations which include volatile components, such as gels or sprays, are appealing from a cosmetic perspective. However, complex formulation effects may result from the use of volatile excipients in topical formulations, particularly when applied at clinically relevant doses
Kyung-Jin Min et al.
Aging cell, 7(2), 199-206 (2008-01-29)
Reduced insulin/insulin-like growth factor (IGF) signaling may be a natural way for the reduction of dietary nutrients to extend lifespan. While evidence challenging this hypothesis is accumulating with Caenorhabditis elegans, for Drosophila melanogaster it is still thought that insulin/IGF and
K Kannathasan et al.
Acta tropica, 120(1-2), 115-118 (2011-07-19)
The vector-borne diseases caused by mosquitoes are one of the major health problems in many countries especially in tropical and sub-tropical countries. The resistance of mosquitoes to synthetic chemicals and environmental toxicity created by the chemicals raised the demand for
M G Soni et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 40(10), 1335-1373 (2002-10-22)
Methyl paraben (CAS No. 99-76-3) is a methyl ester of p-hydroxybenzoic acid. It is a stable, non-volatile compound used as an antimicrobial preservative in foods, drugs and cosmetics for over 50 years. Methyl paraben is readily and completely absorbed through
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