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Key Documents

32071

Supelco

Nafcillin sodium salt

VETRANAL®, analytical standard

Synonyma:

(2S,5R,6R)-6-{[(2-Ethoxy-1-naphthalenyl)carbonyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium salt, 6-(2-Ethoxy-1-naphthamido)penicillin sodium salt

Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen


About This Item

Empirický vzorec (Hillův zápis):
C21H21N2NaO5S
Číslo CAS:
Molekulová hmotnost:
436.46
EC Number:
UNSPSC Code:
41116107
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

storage temp.

2-8°C

InChI

1S/C21H22N2O5S.Na/c1-4-28-13-10-9-11-7-5-6-8-12(11)14(13)17(24)22-15-18(25)23-16(20(26)27)21(2,3)29-19(15)23;/h5-10,15-16,19H,4H2,1-3H3,(H,22,24)(H,26,27);/q;+1/p-1/t15-,16+,19-;/m1./s1

InChI key

AYAPZOUDXCDGIF-FRFVDRIFSA-M

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General description

Chemical structure: ß-lactam
Nafcillin is a penicillin antibiotic used mostly in treating mastitis of cows.

Application

Nafcillin sodium salt (NF-PC) has been used as working standard in HPLC analysis to determine β-lactam antibiotics from milk samples and in LC–MS–MS analysis to determine NF-PC in bovine tissues.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Osvědčení o analýze (COA)

Lot/Batch Number

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Potřebujete-li konkrétní verzi, můžete vyhledat daný certifikát podle čísla dávky nebo čísla šarže.

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Research in microbiology, 160(3), 187-192 (2009-04-16)
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Marin L Schweizer et al.
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The high prevalence of methicillin-resistant S. aureus (MRSA) has led clinicians to select antibiotics that have coverage against MRSA, usually vancomycin, for empiric therapy for suspected staphylococcal infections. Clinicians often continue vancomycin started empirically even when methicillin-susceptible S. aureus (MSSA)
Craig B Whitman et al.
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To report a case of acute interstitial nephritis (AIN) secondary to nafcillin. A 55-year-old Hispanic man (height, 63 in.; weight, 61.2 kg) with a history of deep vein thrombosis in the right lower extremity, hypertension, hyperlipidemia, and hepatitis C infection
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Biofilm infections are frequently caused by Staphylococcus epidermidis, are resistant to antimicrobial agents, and adversely affect patient outcomes. We evaluated farnesol (FSL), the Candida quorum-sensing molecule, on S. epidermidis biofilms, in vitro and in vivo. We evaluated ED50, ED75, and

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