235989

Brij^® L4

average M_n ~362

• Synonyma: Polyethylene glycol dodecyl ether, Polyoxyethylene (4) lauryl ether
• Lineární vzorec: (C₂₀H₄₂O₅)_n
• Číslo CAS: 9002-92-0
• MDL number: MFCD00043063
• UNSPSC Code: 12161900
• PubChem Substance ID: 24854130
• NACRES: NA.21

Vlastnosti

• description: non-ionic
• Quality Level: 200
• mol wt: average M_n ~362
• refractive index: n20/D 1.451 (lit.)
• density: 0.95 g/mL at 25 °C (lit.)
• HLB: 9
• SMILES string: CCCCCCCCCCCCOCCOCCOCCOCCO
• InChI: 1S/C20H42O5/c1-2-3-4-5-6-7-8-9-10-11-13-22-15-17-24-19-20-25-18-16-23-14-12-21/h21H,2-20H2,1H3
• InChI key: WPMWEFXCIYCJSA-UHFFFAOYSA-N

Popis

General description

Brij^® L4 is a non-ionic surfactant. It comprises an alkyl (C12) tail attached to an oxyethylene headgroup.

Application

Brij^® L4 has been used:

• as a surfactant for the synthesis of copper(I) oxide (Cu₂O) spherical nanoparticles using a microemulsion technique
• as a non-ionic surfactant for preparing reverse micelles to synthesize Pt₃Co alloy nanoparticles
• as a surfactant to enhance the efficiency of interfacial coupling of hydrophobic materials and to make hydrogel

Biochem/physiol Actions

Brij^® L4 exhibits amphiphilic properties. Brij L4 contains hydrophobic and hydrophilic regions that can form micelles and disperse hydrophobic drugs into the core of micelles. This in turn enhances drug solubility. Brij L4 also elicits a strong inhibitory effect against breast cancer resistance protein (BCRP) mediated drug efflux. It inhibits Taq adsorption better when compared to other commonly used surfactants. Brij L4 supports droplet polymerase chain reaction (PCR) in picoliter reaction volumes at standard Taq concentrations.

Legal Information

Brij is a registered trademark of Croda International PLC

Bezpečnostní informace

• pictograms: GHS07,GHS09
• signalword: Warning
• hcodes: H302,H315,H319,H411
• pcodes: P264 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves