P4019

Brij^® S20

• Synonyma: Polyethylene glycol octadecyl ether, Polyoxyethylene (20) stearyl ether
• Lineární vzorec: C₁₈H₃₇(OCH₂CH₂)_nOH, n~20
• Číslo CAS: 9005-00-9
• NACRES: NA.23
• PubChem Substance ID: 24898482
• UNSPSC Code: 12162002
• MDL number: MFCD00074177

Vlastnosti

• form: solid
• Quality Segment: 100
• mp: 44-46 °C (lit.)
• HLB: 15
• SMILES string: CCCCCCCCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
• InChI: 1S/C20H41O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19-22-20-18-21/h2-20H2,1H3
• InChI key: PSEGVHKUPXNGGJ-UHFFFAOYSA-N

Popis

General description

Brij^® S20 is a surfactant that belongs to the class of polyoxyethylene ethers. It is majorly used in pharmaceutical applications to improve the solubility of the drugs. It can also be grafted on a variety of surfaces to enhance the intracellular uptake of dyes.

Application

• Nanostructured lipid carriers for oral delivery of silymarin: Improving its absorption and in vivo efficacy in type 2 diabetes and metabolic syndrome model.: This study utilizes Brij^® S20 to develop nanostructured lipid carriers for oral delivery of silymarin. The findings demonstrate enhanced absorption and efficacy of silymarin in treating type 2 diabetes and metabolic syndrome, highlighting the potential of Brij^® S20 in improving drug delivery systems. (Piazzini et al., 2019).


• Water-stable all-biodegradable microparticles in nanofibers by electrospinning of aqueous dispersions for biotechnical plant protection.: The study uses Brij^® S20 to create water-stable, biodegradable microparticles in nanofibers through electrospinning. These microparticles are designed for biotechnical plant protection, demonstrating the potential of Brij^® S20 in agricultural biotechnology. (Bansal et al., 2012).

Legal Information

Brij is a registered trademark of Croda International PLC

Bezpečnostní informace

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Skladovací třída: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)