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Merck

NXF-50

Natrix® Q Process 600

Natrix® Q Process 600 (460 mL), pack of 1 device

Synonyma:

Natrix® Q Membrane Adsorber


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O této položce

UNSPSC Code:
41115711
eCl@ss:
32011308

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Název produktu

Natrix® Q Process 600,

ligand

quaternary amine

product line

Natrix®

parameter

2.3-11.5 L/min flow rate

bed H

0.5 mm

bed volume

460 mL

matrix active group

Macroporous polymer

pore size

0.4 μm pore size

capacity

92 g binding capacity (BSA)(per device)

Quality Level

separation technique

strong anion exchange

shipped in

ambient

General description

Strong anion exchange chromatography membrane design to purify biomolecules with a high density of quaternary amine ligand the enables fast flow rates and high throughput at high loads while maintaining excellent impurity reduction
With a revolutionary three-dimensional macroporous hydrogel structure that provides a high density of binding sites and rapid mass transfer, Natrix® chromatography membranes deliver binding capacity that exceeds resin-based columns with fast flow rates typical of traditional membrane adsorbers. This combination of performance and speed in a single-use, plug-and-play device format enables low-risk, scalable solutions for efficient biomolecule purification

Natrix® Q chromatography membrane is a high productivity strong anion exchange membrane designed for biomolecule purification. The unique Natrix® Q chromatography membrane is a porous polyacrylamide hydrogel containing a high density of pendant quaternary ammonium (Q) binding groups that are directly polymerized within the an inert, macroporous membrane scaffold. The interconnected pore structure and high functional group density enables fast flow rates (seconds of residence time) with impressive throughput to extremely high loads while maintaining excellent impurity reduction across a wide range of buffer conditions. The Natrix® Q chromatography membrane design delivers improvements in productivity, flexibility, and process robustness and economics for any bioprocess design. The Natrix® Q Process 600 is process scale device designed for full-scale clinical and commercial manufacturing.

mAb nominal polishing capacity: 4600 g

Membrane configuration: Pleated

1 device per package

Features and Benefits

Natrix® Q membrane adsorber provides users with:

  • High density of quaternary amine binding sites enabling rapid mass transfer
  • High binding capacity even at fast flow rates
  • Combination of performance and speed in, single use, plug-and-play device format enables low risk, scalable solutions for efficient biomolecule purification.

Packaging

Double bagged

Legal Information

NATRIX is a registered trademark of Merck KGaA, Darmstadt, Germany

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