1.51451

Chromolith^® RP-18 endcapped (monolithic) HPLC Columns

L × I.D. 5 mm x 4.6 mm Guard Cartridges (3 pieces)

• Synonyma: Chromolith^® RP-18 endcapped 5-4.6 guard cartridges (3 pieces)
• UNSPSC Code: 41115709
• NACRES: SB.52

Vlastnosti

• product name: Chromolith^® RP-18 endcapped, L × I.D. 5 mm x 4.6 mm guard cartridges (3 pieces)
• material: PEEK column
• Quality Level: 100
• agency: suitable for USP L1
• product line: Chromolith^®
• feature: endcapped
• packaging: pkg of 3 ea
• extent of labeling: 18% Carbon loading
• parameter: 400 bar pressure; 45 °C max. temp.
• technique(s): HPLC: suitable; LC/MS: suitable; mass spectrometry (MS): suitable (High)
• column L × I.D.: 0.5 cm × 4.6 mm
• matrix: monolithic silica
• matrix active group: C18 bonding phase
• pore size: 13 nm mesoporosity; 2 μm macroporosity
• operating pH range: 2-7.5
• separation technique: reversed phase
• storage temp.: no temp limit

Popis

General description

Although the Chromolith^® columns are well known for their robustness and longevity, guard columns are available to prolong the lifespan of Chromolith^® analytical columns even further. These guard cartridges require a special holder.
Chromolith^® RP-18 endcapped 5-4.6 guard cartridges are extremely easy to use. The guard cartridges are simply added directly in front of the main column to protect it from chemical or mechanical contamination. Due to the benefits of monolithic technology, and the convenience of Chromolith^® guard columns, they are also popular for use with classical particulate columns. Moreover, guard columns can be used as trap columns when large sample volumes are to be injected. Guard columns should be changed frequently in order to avoid excessive accumulation of impurities.

Chromolith^® columns are made of monolithic silica with a characteristic bimodal pore structure.

Chromolith^® RP-18 endcapped 5-4.6 guard cartridges are used with the Chromolith^® Guard Cartridge Holder 5 mm x 4.6 mm [1.52032]

Learn more:
Brochure: Race through your Separations on Any System. Chromolith^® Monolithic Silica HPLC Columns

All Supelco HPLC Columns, including monolithic Chromolith^® columns, are fully compatible to all HPLC and UHPLC Instruments.
Supelco HPLC Products: The Best Choice for Any LC Instrument

Application

• Rapid Determination of 30 Polyphenols in Tongmai Formula: This study utilized the Chromolith^® RP-18 endcapped column in a liquid chromatography-tandem mass spectrometry setup to analyze 30 polyphenolic compounds in a traditional Chinese medicine formula, demonstrating its application in pharmaceutical analysis and quality control of complex herbal formulations (Wang et al., 2017).


• Ultra-fast gradient LC method for omeprazole analysis using a monolithic column: The Chromolith^® RP-18 endcapped column was employed in an ultra-fast gradient liquid chromatography method for the analysis of omeprazole in enteric-coated pellets, highlighting its efficiency in pharmaceutical quality control and rapid method development (Borges et al., 2010).

Analysis Note

visual control (for delivery): passes test

Legal Information

Chromolith is a registered trademark of Merck KGaA, Darmstadt, Germany