1.07428

Propyl 4-hydroxybenzoate sodium salt

EMPROVE^® ESSENTIAL, Ph. Eur., BP, NF

• Synonyma: Propyl 4-hydroxybenzoate sodium salt, 4-Hydroxybenzoic acid propyl ester sodium salt, Propylparaben sodium salt
• Empirický vzorec (Hillův zápis): C₁₀H₁₁NaO₃
• Číslo CAS: 35285-69-9
• Molekulová hmotnost: 202.18
• MDL number: MFCD00016477
• UNSPSC Code: 12352108
• EC Index Number: 252-488-1

Vlastnosti

• agency: BP; NF; Ph. Eur.
• Quality Level: 500
• product line: EMPROVE^® ESSENTIAL
• form: solid
• pH: 9.5-10.5 (20 °C, 1 g/L in H₂O)
• mp: 302 °C
• density: 1.24 g/cm³ at 25 °C
• application(s): liquid formulation; ophthalmics; pharmaceutical; semi-solid formulation; solid formulation
• storage temp.: 15-25°C
• InChI: 1S/C10H12O3.Na/c1-2-7-13-10(12)8-3-5-9(11)6-4-8;/h3-6,11H,2,7H2,1H3;/q;+1/p-1
• InChI key: IXMINYBUNCWGER-UHFFFAOYSA-M

Popis

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Propyl 4-hydroxybenzoate has antimicrobial characteristics and is used as preservative in pharmaceutical formulations and cosmetics. It can be combined with other parabens like methyl 4-hydroxybenzoate or ethyl 4-hydroxybenzoate. The sodium salt provides improved solubility in water compared to standard propyl 4-hydroxybenzoate.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

Bezpečnostní informace

• pictograms: GHS05
• signalword: Danger
• hcodes: H318
• pcodes: P280 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3