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E-016

Supelco

Ethyl-β-D-glucuronide

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirický vzorec (Hillův zápis):
C8H14O7
Číslo CAS:
Molekulová hmotnost:
222.19
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

SMILES string

O[C@H]1[C@H](O)[C@@H](C(O)=O)O[C@@H](OCC)[C@@H]1O

InChI

1S/C8H14O7/c1-2-14-8-5(11)3(9)4(10)6(15-8)7(12)13/h3-6,8-11H,2H2,1H3,(H,12,13)/t3-,4-,5+,6-,8+/m0/s1

Inchi Key

IWJBVMJWSPZNJH-UQGZVRACSA-N

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General description

This Certified Reference Material is widely used in forensic analysis and clinical toxicology applications to determine blood alcohol content.

Ethyl-β-D-glucuronide (EtG) is a water-soluble and stable metabolite of ethanol, used as a routine biomarker in alcohol abuse monitoring. A very small fraction of ethanol undergoes degradation to EtG, and it can be detected in body fluids as well as hair.

Application

The certified reference solution (CRM) in solution can also be used as follows:

  • Multi-residue analysis of different alcohol metabolites in human blood plasma and urine samples by ultra-high performance liquid chromatography (UHPLC) combined with tandem mass spectrometry (MS/MS)
  • Optimization of a supercritical fluid chromatography-tandem mass spectrometric (SFC-MS/MS) method for the separation and quantification of highly polar drugs and their metabolites using an ion-exchange stationary phase from human urine samples
  • Evaluation of a paired ion electrospray ionization mass spectrometric (PIESI-MS) approach coupled with high performance liquid chromatographic (HPLC) procedure for the detection and measurement of drug metabolites in urine samples
  • Assess the impact of sample preparation of hair samples on the quantitative analysis of ethyl-β-D-glucuronide by ultra-high performance liquid chromatography-electrospray ionization-tandem mass spectrometry
  • Analysis of ethyl-β-D-glucuronide as a urinary biomarker in human urine samples by a benchtop gas chromatograph coupled with a mass spectrometer (GC-MS)

Features and Benefits

  • Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
  • Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
  • Rigorously tested through real-time stability studies to ensure accuracy and shelf life
  • Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
  • Flame sealed under argon into ampoules for long-term shelf life
  • Offered in a convenient, DEA-exempt format to improve laboratory efficiency

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Č. produktu
Popis
Stanovení ceny

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup


Osvědčení o analýze (COA)

Vyhledejte osvědčení Osvědčení o analýze (COA) zadáním čísla šarže/dávky těchto produktů. Čísla šarže a dávky lze nalézt na štítku produktu za slovy „Lot“ nebo „Batch“.

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Navštívit knihovnu dokumentů

A versatile UHPLC-MSMS method for simultaneous quantification of various alcohol intake related compounds in human urine and blood
Monosik R and Dragsted LO
Analytical Methods : Advancing Methods and Applications, 8, 6865-6871 (2016)
RN in rehab program challenged flawed alcohol tests. Case on point: Berry v. National Medical Services, Inc., 257 P.3d 287 (8/12/2011)-KS.
Nursing law's Regan report, 52(5), 2-2 (2012-10-18)
Solfrid Hegstad et al.
Journal of analytical toxicology, 37(4), 227-232 (2013-03-08)
In cases of sexual assault, victims often present too late for the detection of ethanol in biological samples. An ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS-MS) method was developed and validated for the determination of ethyl glucuronide (EtG) and ethyl sulfate
Jeremy N Matlow et al.
Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharamcologie clinique, 19(3), e473-e482 (2012-11-06)
Ethyl glucuronide (EtG) is arising as a promising biomarker of heavy prenatal alcohol exposure, however its transfer across the human placenta is still unclear and is currently being investigated using the ex vivo placental perfusion model. This model allows for
J N Matlow et al.
Placenta, 34(4), 369-373 (2013-02-05)
Alcohol consumption during pregnancy can lead to Fetal Alcohol Spectrum Disorder (FASD), and because maternal self-reports are often unreliable, biomarkers of alcohol use are sometimes necessary to accurately determine fetal risk. Ethyl glucuronide (EtG), a direct metabolite of ethanol, has

Sortimentní položky

This study is aimed at developing and validating an LC-ESI-ion trap-MS/MS method for identification and quantification of ethyl glucuronide (EtG) and ethyl sulfate (EtS) as ethanol biomarkers for urine analysis.

Náš tým vědeckých pracovníků má zkušenosti ve všech oblastech výzkumu, včetně přírodních věd, materiálových věd, chemické syntézy, chromatografie, analytiky a mnoha dalších..

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