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901397

Sigma-Aldrich

Poly(ethylene glycol) linear dendrimer

NHBoc terminated, PEG Mn 6000, generation 4

Synonyma:

Dendron bifunctionalized PEG, PFD-G4-PEG6k-NHBoc, Polyethylene glycol

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About This Item

Empirický vzorec (Hillův zápis):
C678H1202N32O323
Molekulová hmotnost:
14970.82
UNSPSC Code:
51171641
NACRES:
NA.23

Quality Level

100

form

solid

mol wt

PEG Mn 6000

color

white to off-white

storage temp.

−20°C

General description

  • Polymer architecture: Dendron-functionalized PEG
  • Generation: 4
  • PEG Average Mn: 6,000
  • End group functionality: Boc-protected amine
  • No. surface groups: 32
  • Calculated mol. wt.: 14970.98 g/mol
  • Boc: tert-Butyloxycarbonyl
  • Bis-MPA: 2,2-bis(hydroxymethyl)propionic acid

Application

Bis-MPA (or 2,2-bis(methylol)propionic acid) is an aliphatic, pro-chiral molecule comprised of two hydroxyls and one carboxylic group that has been used in the synthesis of many different types of polymers. Dendrons synthesized from bis-MPA are biodegradable and have low cytotoxicity, making them well suited for use in biological research applications. These materials have been used in many applications such as signal amplification in bioassays and in drug delivery applications. PEG-core dendrimers feature excellent solubility in water and a high degree of functionality per PEG chain, making them strong candidates for advanced drug delivery systems or as targeting vessels. Additionally, the terminal amine groups can readily be used in EDC or DCC coupling reactions (after Boc deprotection) with carbonyl-containing compounds, to yield highly functionalized materials for a variety of biomedical applications.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Osvědčení o analýze (COA)

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