775797

Isopropylmagnesium bromide solution

0.75 M in THF

• Synonyma: 1-Methylethylmagnesium bromide, 2-Propylmagnesium bromide, iso-Propylmagnesium bromide, Bromoisopropylmagnesium
• Lineární vzorec: (CH₃)₂MgBr
• Číslo CAS: 920-39-8
• Molekulová hmotnost: 147.30
• MDL number: MFCD00672110
• UNSPSC Code: 12352103
• PubChem Substance ID: 329767789
• NACRES: NA.22

Vlastnosti

• form: solution
• Quality Level: 100
• reaction suitability: reaction type: Grignard Reaction
• concentration: 0.75 M in THF
• density: 0.982 g/mL at 25 °C
• storage temp.: 2-8°C
• SMILES string: CC(C)[Mg]Br
• InChI: 1S/C3H7.BrH.Mg/c1-3-2;;/h3H,1-2H3;1H;/q;;+1/p-1
• InChI key: UCJIVFREPMUZDC-UHFFFAOYSA-M

Popis

Application

• Preparation of isopropylmagnesium bromide solutions: In this study, various concentrations of isopropylmagnesium bromide solutions were prepared, detailing their stability and reactivity for use in palladium-catalyzed cross-coupling reactions and other synthetic applications (Vulović et al., 2017).
• Reductive coupling of amides: This research discusses the reductive functionalization of tertiary amides using isopropylmagnesium bromide, providing a novel method for amine synthesis, which is crucial for pharmaceutical chemistry (Xie and Dixon, 2017).
• Synthesis of 1, 2, 3-triazoles: The study explores the use of isopropylmagnesium bromide in the synthesis of 1, 2, 3-triazoles through Grignard reactions, highlighting its role in protecting azides during the reaction process (Namioka et al., 2023).
• Disposable cartridge concept for Grignard reagents: This paper introduces a novel disposable cartridge for the on-demand synthesis of Grignard reagents, including isopropylmagnesium bromide, enhancing the safety and scalability of Grignard reactions (Berton et al., 2020).

Packaging

The 25 mL Sure/Seal^™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.

Legal Information

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

Bezpečnostní informace

• pictograms: GHS02,GHS08,GHS05,GHS07
• signalword: Danger
• hcodes: H225,H260,H302,H314,H335,H336,H351
• pcodes: P210 - P231 + P232 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3 - Water-react 1
• target_organs: Respiratory system
• supp_hazards: EUH014,EUH019
• Storage Class: 4.3 - Hazardous materials which set free flammable gases upon contact with water
• wgk_germany: WGK 1
• flash_point_f: -22.0 °F - closed cup
• flash_point_c: -30 °C - closed cup