496065

2,6-Bis[(4R)-4-phenyl-2-oxazolinyl]pyridine

98%

• Synonyma: (R,R)-2,6-Bis(4,5-dihydro-4-phenyl-2-oxazolyl)pyridine, (R,R)-2,6-Bis(4-phenyl-2-oxazolinyl)pyridine
• Empirický vzorec (Hillův zápis): C₂₃H₁₉N₃O₂
• Číslo CAS: 128249-70-7
• Molekulová hmotnost: 369.42
• MDL number: MFCD01863585
• UNSPSC Code: 12352005
• PubChem Substance ID: 24873016
• NACRES: NA.22

Vlastnosti

• assay: 98%
• optical activity: [α]22/D 187°, c = 1 in methylene chloride
• mp: 171-175 °C (lit.)
• SMILES string: C1OC(=N[C@@H]1c2ccccc2)c3cccc(n3)C4=N[C@@H](CO4)c5ccccc5
• InChI: 1S/C23H19N3O2/c1-3-8-16(9-4-1)20-14-27-22(25-20)18-12-7-13-19(24-18)23-26-21(15-28-23)17-10-5-2-6-11-17/h1-13,20-21H,14-15H2/t20-,21-/m0/s1
• InChI key: HLHBIMJNCKZZQO-SFTDATJTSA-N

Popis

Application

2,6-Bis[(4R)-4-phenyl-2-oxazolinyl]pyridine [Pybox] may be used as a chiral ligand in the copper-catalyzed enatioselective arylation of N-arylated tetrahydroisoquinolines (THIQs) with arylboronic acids in the presence of a photoredox catalyst.

Bezpečnostní informace

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves