142824
1-Methyl-1-cyclohexanecarboxylic acid
99%
Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen
About This Item
Lineární vzorec:
CH3C6H10CO2H
Číslo CAS:
Molekulová hmotnost:
142.20
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Doporučené produkty
assay
99%
form
solid
bp
234 °C (lit.)
mp
36-39 °C (lit.)
functional group
carboxylic acid
SMILES string
CC1(CCCCC1)C(O)=O
InChI
1S/C8H14O2/c1-8(7(9)10)5-3-2-4-6-8/h2-6H2,1H3,(H,9,10)
InChI key
REHQLKUNRPCYEW-UHFFFAOYSA-N
Související kategorie
General description
1-Methyl-1-cyclohexanecarboxylic acid is the structural analog of valproic acid and its pharmacokinetic action has been studied in female Sprague-Dawley rats.
Application
1-Methyl-1-cyclohexanecarboxylic acid was used as internal standard during the determination of valproic acid metabolites.
Biochem/physiol Actions
1-Methyl-1-cyclohexanecarboxylic acid is an anticonvulsant drug and causes maturation of murine neuroblastoma cells in vitro.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
213.8 °F - closed cup
flash_point_c
101.00 °C - closed cup
ppe
Eyeshields, Gloves, type N95 (US)
Vyberte jednu z posledních verzí:
Osvědčení o analýze (COA)
Lot/Batch Number
Nevidíte správnou verzi?
Potřebujete-li konkrétní verzi, můžete vyhledat daný certifikát podle čísla dávky nebo čísla šarže.
Již tento produkt vlastníte?
Dokumenty související s produkty, které jste v minulosti zakoupili, byly za účelem usnadnění shromážděny ve vaší Knihovně dokumentů.
S A Fischkoff et al.
Journal of biological response modifiers, 3(2), 132-137 (1984-01-01)
The anticonvulsant drug 1-methyl-1-cyclohexanecarboxylic acid ( MCCA ) has been shown to cause maturation of murine neuroblastoma cells in vitro at concentrations that are pharmacologically achievable. HL-60 human promyelocytic leukemia cells cultured with this drug underwent a dose-dependent decrease in
P Benoit et al.
Neuropharmacology, 21(12), 1239-1244 (1982-12-01)
The effect of an anticonvulsant compound (Simiand, Ferrandes, Lacolle and Eymard, 1979), 1-methyl cyclohexane carboxylic acid (CCA), upon the electrical activity of Purkinje cells (PCs) was studied in the cerebellar cortex of the rat in vivo. Cyclohexane carboxylic acid (200-400
J L Vayssiere et al.
Biochemical and biophysical research communications, 140(3), 789-796 (1986-11-14)
CCA, a potent neuroblastoma differentiation inducer, was shown by oxygraphic measurements to reduce significantly the O2 consumption of whole neuroblastoma cells as of mitochondria purified from neuroblastoma or mouse cortex. The effect of CCA on the respiration was compared to
A J Sadeque et al.
The Journal of pharmacology and experimental therapeutics, 283(2), 698-703 (1997-11-14)
Cytochrome P450-dependent desaturation of the anticonvulsant drug valproic acid (VPA) results in formation of the hepatotoxin, 4-ene-VPA. Polytherapy with other anticonvulsants which are known P450 inducers increases the flux through this bioactivation pathway. The aim of the present study was
J C Larcher et al.
Experimental cell research, 203(1), 72-79 (1992-11-01)
Adriamycin, an anticancer agent acting on topoisomerase II, promotes the arrest of cell division and neurite extension in a "neurite-minus" murine neuroblastoma cell line, N1A-103. This morphological differentiation is accompanied by a blockade in the S phase of the cell
Náš tým vědeckých pracovníků má zkušenosti ve všech oblastech výzkumu, včetně přírodních věd, materiálových věd, chemické syntézy, chromatografie, analytiky a mnoha dalších..
Obraťte se na technický servis.