Z4277

Zileuton

≥98% (HPLC)

• Sinónimos: (±)-N-hydroxy-N-(1-benzo[b]thien-2-ylethyl)urea
• Fórmula empírica (notación de Hill): C₁₁H₁₂N₂O₂S
• Número de CAS: 111406-87-2
• Peso molecular: 236.29
• MDL number: MFCD00866097
• UNSPSC Code: 12352200
• PubChem Substance ID: 329831613
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to off-white
• solubility: DMSO: ≥20 mg/mL at ~60 °C (warm up to 60 C for 5min)
• originator: Abbott
• storage temp.: room temp
• SMILES string: CC(N(O)C(N)=O)c1cc2ccccc2s1
• InChI: 1S/C11H12N2O2S/c1-7(13(15)11(12)14)10-6-8-4-2-3-5-9(8)16-10/h2-7,15H,1H3,(H2,12,14)
• InChI key: MWLSOWXNZPKENC-UHFFFAOYSA-N
• Gene Information: human ... ALOX5(240)

Descripción

Biochem/physiol Actions

Zileuton is an anti-asthmatic, an inhibitor of 5-lipoxygenase; the initial enzyme in the biosynthesis of leukotrienes from arachidonic acid.

Features and Benefits

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Información de seguridad

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H361d
• pcodes: P202 - P264 - P270 - P280 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable