27285

Ácido etilenodiaminotetraacético disodium salt dihydrate

meets analytical specification of Ph. Eur., BP, USP, FCC, 99.0-101.0%

• Sinónimos: EDTA disodium salt, EDTA-Na₂, Edatamil, Edetato disodium salt dihydrate, Etilenodiaminotetraacetato de disodio dihydrate, Sequestrene Na₂
• Fórmula empírica (notación de Hill): C₁₀H₁₄N₂Na₂O₈ · 2H₂O
• Número de CAS: 6381-92-6
• Peso molecular: 372.24
• Beilstein/REAXYS Number: 3900609
• EC Number: 205-358-3
• UNSPSC Code: 12352107
• PubChem Substance ID: 24856480
• NACRES: NA.77

Propiedades

• agency: tested according to BP; tested according to Ph. Eur.; tested according to USP
• Quality Level: 200
• reg. compliance: tested according to FCC
• assay: 99.0-101.0%
• form: crystals
• quality: meets analytical specification of Ph. Eur., BP, USP, FCC
• reaction suitability: reagent type: chelator
• impurities: residual solvents, complies; ≤0.001% cyanide (CN); ≤0.001% heavy metals (as Pb); ≤0.1% nitrilotriacetic acid (HPLC) (HPLC)
• loss: 8.7-11.4% loss on drying, 200 °C, 3 h
• pH: 4-5 (20 °C, 5%)
• mp: 248 °C (dec.) (lit.)
• solubility: water: soluble 100 g/L at 20 °C
• anion traces: chloride (Cl^-): ≤100 mg/kg; sulfate (SO₄^2-): ≤500 mg/kg
• cation traces: As: ≤1 mg/kg; Ca:, in accordance; Fe: ≤10 mg/kg; Pb: ≤10 mg/kg
• application(s): pharmaceutical (small molecule)
• SMILES string: O.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O
• InChI: 1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2
• InChI key: OVBJJZOQPCKUOR-UHFFFAOYSA-L

Descripción

General description

Ethylenediaminetetraacetic acid disodium salt dihydrate, referred to as EDTA is a widely used chelator of divalent cations like Ca⁺². It can inhibit proteases dependent on metal ions, such as, calcium-dependent cysteine proteases. EDTA also acts as a chelator of the Zn ion, inhibiting metalloproteases that require zinc for activity.

Application

Ethylenediaminetetraacetic acid disodium salt dihydrate has been used along with Na₂HPO4 and citric acid for preparing Na₂EDTA-McIlvaine buffer. Aqueous solution of Ethylenediaminetetraacetic acid disodium salt dihydrate has also been used for photocatalytic hydrogen production

Quelante de cationes divalentes. Inhibe las enzimas, como las metaloproteasas, que requieren cationes divalentes para ser activas.

Other Notes

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Información de seguridad

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H332,H373
• pcodes: P260 - P271 - P304 + P340 + P312 - P314 - P501
• Hazard Classifications: Acute Tox. 4 Inhalation - STOT RE 2 Inhalation
• target_organs: Respiratory Tract
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)