PHR1068

Ácido etilenodiaminotetraacético disodium salt dihydrate

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinónimos: EDTA disodium salt, EDTA-Na₂, Edatamil, Edetato disodium salt dihydrate, Etilenodiaminotetraacetato de disodio dihydrate, Sequestrene Na₂
• Fórmula empírica (notación de Hill): C₁₀H₁₄N₂Na₂O₈ · 2H₂O
• Número de CAS: 6381-92-6
• Peso molecular: 372.24
• Beilstein/REAXYS Number: 3900609
• EC Number: 205-358-3
• UNSPSC Code: 41116107
• NACRES: NA.24

Propiedades

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• agency: traceable to Ph. Eur. D2900000; traceable to USP 1233009
• API family: edta
• CofA: current certificate can be downloaded
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• mp: 248 °C (dec.) (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• Storage temp.: 2-30°C
• SMILES string: O.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O
• InChI: 1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2
• Inchi Key: OVBJJZOQPCKUOR-UHFFFAOYSA-L

Descripción

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Ethylenediaminetetraacetic acid disodium salt dehydrate may be used as a reference standard in validating the potential antioxidant activity and the total phenolic content of samples of seaweed extract via metal chelation technique using ferrous ion-chelating ability assay.

Ethylenediaminetetraacetic acid disodium salt dihydrate may be used as a pharmaceutical reference standard for the determination of ethylenediaminetetraacetic acid (EDTA) in pharmaceutical formulations using ion chromatography with suppressed conductimetric detection.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Quelante de cationes divalentes. Inhibe las enzimas, como las metaloproteasas, que requieren cationes divalentes para ser activas.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA5634 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

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Información de seguridad

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H332,H373
• pcodes: P260 - P271 - P304 + P340 + P312 - P314 - P501
• Hazard Classifications: Acute Tox. 4 Inhalation - STOT RE 2 Inhalation
• target_organs: Respiratory Tract
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable