337358

4-Iodo-2-methylphenol

97%

• Sinónimos: 4-Iodo-o-cresol
• Fórmula lineal: IC₆H₃(CH₃)OH
• Número de CAS: 60577-30-2
• Peso molecular: 234.03
• MDL number: MFCD00075092
• UNSPSC Code: 12352100
• PubChem Substance ID: 24860475
• NACRES: NA.22

Propiedades

• assay: 97%
• bp: 105-110 °C/2 mmHg (lit.)
• mp: 67-68 °C (lit.)
• SMILES string: Cc1cc(I)ccc1O
• InChI: 1S/C7H7IO/c1-5-4-6(8)2-3-7(5)9/h2-4,9H,1H3
• InChI key: WSBDSSKIWDFOBQ-UHFFFAOYSA-N

Descripción

General description

4-Iodo-2-methylphenol was prepared by direct iodination of 2-methylphenol in aqueous alcohol solvents by the action of a reagent prepared in situ from sodium hypochlorite and sodium iodide.

Application

4-Iodo-2-methylphenol was used as starting reagent in the synthesis of an agonist for the peroxisome proliferator-activated receptor δ (PPARδ) GW501516, a potential antiobesity drug.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves