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T4009

Sigma-Aldrich

Ácido taurocólico sodium salt hydrate

≥95% (HPLC)

Sinónimos:

Taurocolato de sodio hydrate, Ácido 2-[(3α,7α,12α-Trihidroxi-24-oxo-5β-colan-24-il) amino] etanosulfónico, Ácido 3α,7α,12α-trihidroxi-5β-colan-24-oico N-(sulfoetil)amida

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250 MG
$54.500
1 G
$93.500
5 G
$308.000
25 G
$1.160.000
100 G
$3.280.000

$54.500

Fecha estimada de envío21 de mayo de 2025

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250 MG
$54.500
1 G
$93.500
5 G
$308.000
25 G
$1.160.000
100 G
$3.280.000

About This Item

Fórmula empírica (notación de Hill):
C26H44NNaO7S · xH2O
Número de CAS:
345909-26-4
Peso molecular:
537.68 (anhydrous basis)
Número CE:
205-653-7
Número MDL:
MFCD00150819
Código UNSPSC:
12161900
ID de la sustancia en PubChem:
24900186
NACRES:
NA.25

$54.500

Fecha estimada de envío21 de mayo de 2025

Solicitar un pedido a granel

origen biológico

synthetic (organic)

descripción

anionic

Ensayo

≥95% (HPLC)

Formulario

powder

mol peso

micellar avg mol wt 2100

número de agregación

4

CMC

3-11 mM (20-25°C)

grupo funcional

sulfonic acid

Condiciones de envío

ambient

temp. de almacenamiento

room temp

cadena SMILES

[Na+].[H]O[H].[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])C[C@H](O)[C@]4(C)[C@H](CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(=O)NCCS([O-])(=O)=O

InChI

1S/C26H45NO7S.Na.H2O/c1-15(4-7-23(31)27-10-11-35(32,33)34)18-5-6-19-24-20(14-22(30)26(18,19)3)25(2)9-8-17(28)12-16(25)13-21(24)29;;/h15-22,24,28-30H,4-14H2,1-3H3,(H,27,31)(H,32,33,34);;1H2/q;+1;/p-1/t15-,16+,17-,18-,19+,20+,21-,22+,24+,25+,26-;;/m1../s1

Clave InChI

RDAJAQDLEFHVNR-NEMAEHQESA-M

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Descripción general

Taurocholic acid sodium salt hydrate is a bile acid with detergent capabilities. [1]

Aplicación

Detergente aniónico utilizado para solubilización de proteínas.
Taurocholic acid sodium salt hydrate has been used in a study to assess the adsorption of bile acids and salts to vegetable fibrous tissue. [2] It has also been used in a study to investigate a method for determination of conjugated and unconjugated bile salts in serum and jejunal fluid. [3]

Acciones bioquímicas o fisiológicas

SAL biliar no sulfatada.
Sal biliar no sulfatada, sustrato de transporte fisiológico para la bomba de exportación de sales biliares/hermana de Pgp (BSEP/spgp), cotransportador de Na(+)/taurocolato (NTCP) y MRP3 en los canalículos hepáticos.

Nota de preparación

Synthesized from cholic acid

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
0000430898
0000430898
0000420920
0000420919
0000420920

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Studies on the adsorption of bile salts to non-absorbed components of diet.
M A Eastwood et al.
Biochimica et biophysica acta, 152(1), 165-173 (1968-01-10)
Yanxia Wei et al.
BMC infectious diseases, 19(1), 46-46 (2019-01-13)
Clostridium difficile (C. difficile) is a main cause of antibiotic-associated diarrhoea in humans. Several studies have been performed to reveal the prevalence rate of C. difficile in cats and dogs. However, little is known about the epidemiology of C. difficile
Studies on the Antibacterial Properties of the Bile Acids and some Compounds Derived from Cholanic Acid
M. Stacey and M. Webb
Proc. Royal Soc. Lond. B., 134, 523-523 (1947)
Theresa D Ho et al.
Infection and immunity, 82(6), 2345-2355 (2014-03-26)
Clostridium difficile is a clinically important pathogen and the most common cause of hospital-acquired infectious diarrhea. Expression of the C. difficile gene csfV, which encodes σ(V), an extracytoplasmic function σ factor, is induced by lysozyme, which damages the peptidoglycan of
A Tangerman et al.
Clinica chimica acta; international journal of clinical chemistry, 159(2), 123-132 (1986-09-15)
A reliable method is described for the determination of conjugated and unconjugated bile acids in serum and jejunal fluid. Bile acids are extracted using reverse-phase octadecylsilane bonded silica cartridges and are separated into their unconjugated and conjugated fractions using the
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Questions

1–2 of 2 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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