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G5918

Sigma-Aldrich

GR 113808

≥98% (HPLC), solid

Sinónimos:

1-[2-[(Methylsulfonyl)-amino]ethyl]-4-piperidinyl]methyl 1-methyl-1H-indole-3-carboxylate

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About This Item

Fórmula empírica (notación de Hill):
C19H27N3O4S
Número de CAS:
144625-51-4
Peso molecular:
393.50
Número MDL:
MFCD00912901
Código UNSPSC:
12352200
ID de la sustancia en PubChem:
24278311
NACRES:
NA.77

Ensayo

≥98% (HPLC)

Formulario

solid

color

white to light pink

solubilidad

DMSO: >20 mg/mL

emisor

GlaxoSmithKline

temp. de almacenamiento

2-8°C

cadena SMILES

Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c3ccccc13

InChI

1S/C19H27N3O4S/c1-21-13-17(16-5-3-4-6-18(16)21)19(23)26-14-15-7-10-22(11-8-15)12-9-20-27(2,24)25/h3-6,13,15,20H,7-12,14H2,1-2H3

Clave InChI

MOZPSIXKYJUTKI-UHFFFAOYSA-N

Información sobre el gen

human ... HTR4(3360)
rat ... Htr3a(79246) , Htr4(25324)

Aplicación

GR 113808 has been used as a serotonin receptor 4 (5-HT4R) blocker to study its effects on the calcium (Ca2+) transients in rat ventricular cardiomyocytes. It has also been used as a 5-HT4R antagonist to study its effects on de novo enteric neurogenesis in post-embryonic zebrafish.

Acciones bioquímicas o fisiológicas

GR 113808 is a 5-HT4 serotonin receptor antagonist.

Características y beneficios

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Información legal

Sold for research purposes under agreement from Glaxo­Smith­Kline

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
0000134836
0000099426
0000083061
0000083073
0000066441

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Sigma-Aldrich

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Roche

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