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L6250

Lithocholic acid

≥95%

Sinónimos:

3α-Hydroxy-5β-cholan-24-oic acid, 3α-Hydroxy-5β-cholanic acid, 5β-Cholan-24-oic acid-3α-ol

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A ustedes/SKUDisponibilidadPrecio
10 g
Comprobar disponibilidad del carrito
$122.000
25 g
Comprobar disponibilidad del carrito
$265.000

Acerca de este artículo

Fórmula empírica (notación de Hill):
C24H40O3
Número CAS:
Peso molecular:
376.57
UNSPSC Code:
12352106
NACRES:
NA.25
PubChem Substance ID:
EC Number:
207-099-1
Beilstein/REAXYS Number:
3217757
MDL number:

$122.000


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biological source

bovine bile

Quality Segment

assay

≥95%

mol wt

376.57 g/mol

mp

183-188 °C (lit.)

functional group

carboxylic acid

shipped in

ambient

storage temp.

room temp

SMILES string

[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC(O)=O)[C@@]4(C)CC[C@]3([H])[C@@]1(C)CC[C@@H](O)C2

InChI

1S/C24H40O3/c1-15(4-9-22(26)27)19-7-8-20-18-6-5-16-14-17(25)10-12-23(16,2)21(18)11-13-24(19,20)3/h15-21,25H,4-14H2,1-3H3,(H,26,27)/t15-,16-,17-,18+,19-,20+,21+,23+,24-/m1/s1

InChI key

SMEROWZSTRWXGI-HVATVPOCSA-N

Gene Information

human ... POLA1(5422), TOP2A(7153)
rat ... Polb(29240)

General description

Lithocholic acid is an oligo(ethylene glycol) derivative of bile acid. [1]

Application

Lithocholic acid has been used in a study to assess cholestasis and its action on several organs and tissues in rats. [2] It has also been used in a study to investigate the regulation of hepatic phospholipid and bile acid homeostasis through SMAD3 activation by TGFβ. [3]

Biochem/physiol Actions

Bile Acid

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Este artículo
L0720800BP927700218P
assay

≥95%

assay

-

assay

-

assay

99% (TLC)

storage temp.

room temp

storage temp.

-

storage temp.

2-8°C

storage temp.

−20°C

mol wt

376.57 g/mol

mol wt

-

mol wt

-

mol wt

-

Quality Level

200

Quality Level

-

Quality Level

-

Quality Level

-

biological source

bovine bile

biological source

-

biological source

-

biological source

-

mp

183-188 °C (lit.)

mp

183-188 °C (lit.)

mp

183-188 °C (lit.)

mp

-


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Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Certificados de análisis (COA)

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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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