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B1520

Sigma-Aldrich

Anti-Bovine Albumin antibody produced in rabbit

whole antiserum

Sinónimos:

Anti-Albumin, bovine serum (BSA)

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About This Item

Número MDL:
Código UNSPSC:
12352203
NACRES:
NA.46

origen biológico

rabbit

Nivel de calidad

conjugado

unconjugated

forma del anticuerpo

whole antiserum

tipo de anticuerpo

primary antibodies

clon

polyclonal

contiene

15 mM sodium azide

reactividad de especies

bovine

técnicas

indirect ELISA: 1:200,000
quantitative precipitin assay: 3.0 mg/mL

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

bovine ... Alb(280717)

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Descripción general

Serum albumin in humans is encoded by the gene mapped to human chromosome 4q13.3. Serum albumin is one of the abundant proteins in the blood and has a molecular weight of 66 kDa.
Anti-Bovine Serum Albumin (BSA) was developed in rabbit using purified BSA from Cohn Fraction V as the immunogen. The antiserum has been treated to remove lipoproteins. Strong reactivity with BSA has been determined by immunoelectrophoresis (IEP).

Aplicación

Anti-Bovine Albumin antibody produced in rabbit may be used for ELISA at a working dilution of 1:200,000. The antibody was used for in vitro labeling of albumin present in mammary tissue extract of lactating cow.
It has also been used for the detection of albumin in nanoparticle using scanning transmission electron microscope.

Acciones bioquímicas o fisiológicas

Albumin is the most abundant circulating proteins present in the serum that binds and transports long-chain fatty acid anions, detoxifies unconjugated bilirubin and transports thyroid and steroid hormones.
Human serum albumin as a transporter, is considered as drug delivery vehicle for treating human diseases. Post-translational modifications like glycation and cysteinylation affects the binding functionality of serum albumin. High albumin protein diet has influence on hyperalbuminemia. Low levels of albumin leads to hypoalbuminemia, associated with decreased production and distribution. Hypoalbuminemia is a risk factor for the development of cardiovascular disease.

Forma física

Rabbit Anti-BSA is provided as a liquid containing 15 mM sodium azide as preservative.

Almacenamiento y estabilidad

For continuous use, store at 2-8 °C for up to one month. For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in "frost-free" freezers is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Pedram Madadkar et al.
Journal of pharmaceutical analysis, 8(3), 187-193 (2018-06-21)
Enrichment and immobilization of analytes by chemical bonding or physical adsorption is typically the first step in many commonly used analytical techniques. In this paper, we discuss a permeation drag based technique as an alternative approach for carrying out location-specific
Unraveling the mysteries of serum albumin?more than just a serum protein.
Merlot AM, et al.
Frontiers in Physiology, 5, 299-299 (2014)
Association of serum albumin and atherosclerosis in chronic hemodialysis patients.
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American Journal of Kidney Diseases, 40(4), 721-727 (2002)
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