This product is intended for use as an analytical standard and has not been tested for use in other applications. Currently, there is no Doxorubicin HCl product available that has been tested for in vivo or in vitro use. However, the research grade item, D1515, has been used successfully in mice, as cited in several publications. Please see the links below to review articles that may be of interest:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451836/pdf/PAN_2020_v24n2_11.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036477/
D2975000
Doxorrubicina hydrochloride
European Pharmacopoeia (EP) Reference Standard
Sinónimos:
DOX, Hidroxidaunorrubicina hydrochloride
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About This Item
Fórmula empírica (notación de Hill):
C27H29NO11 · HCl
Número de CAS:
Peso molecular:
579.98
Beilstein:
4229251
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
NACRES:
NA.24
En este momento no podemos mostrarle ni los precios ni la disponibilidad
Productos recomendados
grado
pharmaceutical primary standard
familia API
doxorubicin
fabricante / nombre comercial
EDQM
mp
216 °C (dec.) (lit.)
aplicaciones
pharmaceutical (small molecule)
Formato
neat
cadena SMILES
Cl[H].COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO
InChI
1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22+,27-;/m0./s1
Clave InChI
MWWSFMDVAYGXBV-RUELKSSGSA-N
Información sobre el gen
human ... TOP2A(7153)
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Descripción general
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the Issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.
Produced by certain strains of Streptomyces coeruleorubidus or Streptomyces peucetius or obtained by any other means.
For further information and support please go to the website of the issuing Pharmacopoeia.
Produced by certain strains of Streptomyces coeruleorubidus or Streptomyces peucetius or obtained by any other means.
Aplicación
This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia. Their suitability for any other use is not guaranteed and is the sole responsibility of the user. This standard is not intended for human or animal use.
Established for the preparation of the below-given solutions as per European Pharmacopoeia:
Established for the preparation of the below-given solutions as per European Pharmacopoeia:
- Reference solutions (b) and (c) in the testing of related substances in daunorubicin hydrochloride using liquid chromatography (General text 2.2.29), according to the monograph 0662
- Reference solutions (a) and (c) to test related substances in doxorubicin hydrochloride using liquid chromatography (General text 2.2.29), according to the monograph 0714
- Reference solutions (b) and (c) in the testing of related substances in epirubicin hydrochloride using liquid chromatography (General text 2.2.29), according to the monograph 1590
Envase
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Otras notas
Sales restrictions may apply.
Producto relacionado
Palabra de señalización
Danger
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Acute Tox. 4 Oral - Carc. 1B - Muta. 1B - Repr. 1B
Código de clase de almacenamiento
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
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Certificados de análisis (COA)
Lot/Batch Number
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