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MAB1912

Sigma-Aldrich

Anti-Collagen Type I (COL1A1) Antibody

CHEMICON®, rat monoclonal, M-58

Sinónimos:

Anti-Procollagen Antibody, Clone M-58 Anti-Procollagen, Type I Procollagen Detection

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
En este momento no podemos mostrarle ni los precios ni la disponibilidad

Nombre del producto

Anti-Procollagen Type I Antibody, NT, clone M-58, culture supernatant, clone M-58, Chemicon®

origen biológico

rat

Nivel de calidad

100

forma del anticuerpo

culture supernatant

clon

M-58, monoclonal

reactividad de especies

human

no debe reaccionar con

rat, hamster, mouse

fabricante / nombre comercial

Chemicon®

técnicas

immunohistochemistry: suitable (paraffin)

isotipo

IgG2α

Nº de acceso NCBI

NM_000088.3

Nº de acceso UniProt

P02452

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... COL1A1(1277)

Especificidad

Recognizes Human pro-collagen I. MAB1912 labels the amino-terminal pro-peptide.

Aplicación

Detect Procollagen Type I using this Anti-Procollagen Type I Antibody, N-terminus, clone M-58 validated for use in IH(P).
Immunohistochemistry: 1:10,000-1:50,000 (fresh frozen tissue sections.)

Suitable for formaldehyde/formalin fixed paraffin sections, suggested starting dilution 1:100-1:1000, after treatment with 1% trypsin, 20 minutes at room temperature. Does not stain mature collagen fibers in tissue. Localized intracellularly in cells producing pro-collagen I. Not recommended for Western Blots Optimal working dilutions must be determined by end user.

Nota de análisis

Control
Skin tissue

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 2

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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James W Reinhardt et al.
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Fibrocytes are hematopoietic-derived cells that directly contribute to tissue fibrosis by producing collagen following injury, during disease, and with aging. The lack of a fibrocyte-specific marker has led to the use of multiple strategies for identifying these cells in vivo.
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Danielsen, Patricia L, et al.
Annals of Surgery, 251, 825-831 (2010)
SPARC-induced increase in glioma matrix and decrease in vascularity are associated with reduced VEGF expression and secretion.
Yunker, CK; Golembieski, W; Lemke, N; Schultz, CR; Cazacu, S; Brodie, C; Rempel, SA
International Journal of Cancer. Journal International Du Cancer null
R E B Watson et al.
The British journal of dermatology, 161(2), 419-426 (2009-05-15)
Very few over-the-counter cosmetic 'anti-ageing' products have been subjected to a rigorous double-blind, vehicle-controlled trial of efficacy. Previously we have shown that application of a cosmetic 'anti-ageing' product to photoaged skin under occlusion for 12 days can stimulate the deposition
Libang Yang et al.
JCI insight, 6(9) (2021-04-07)
Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease. We previously identified fibrogenic mesenchymal progenitor cells (MPCs) in the lungs of patients with IPF who serve as drivers of progressive fibrosis. Recent single-cell RNA sequencing work revealed that IPF
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